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Hlcs holocarboxylase synthetase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100752840, updated on 5-Sep-2025
Gene symbol
Hlcs
Gene description
holocarboxylase synthetase
Locus tag
I79_015753
See related
Ensembl:ENSCGRG00015015086
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Try the new Transcripts and proteins table
See Hlcs in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614462.1 (169808..317643)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (3505314..3682276)

NW_003614462.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene phosphatidylinositol glycan anchor biosynthesis class P Neighboring gene SIM bHLH transcription factor 2 Neighboring gene transfer RNA lysine (anticodon CUU)

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables biotin--[biotin carboxyl-carrier protein] ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
biotin--protein ligase
Names
Biotin--protein ligase
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
XP_035315396.1

Length

  • 864

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614462.1 Reference CriGri_1.0 Primary Assembly

    Range
    169808..317643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035459505.1 → XP_035315396.1  biotin--protein ligase isoform X1

    UniProtKB/TrEMBL
    A0A9J7G0N3
    Conserved Domains (3) summary
    cd16442
    Location:605 → 785
    BPL; biotin protein ligase
    pfam02237
    Location:807 → 854
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:336 → 598
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    3505314..3682276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027415648.2 → XP_027271449.1  biotin--protein ligase isoform X5

    UniProtKB/TrEMBL
    A0A8C2MKE1
    Related
    ENSCGRP00015019664.2, ENSCGRT00015024243.2
    Conserved Domains (3) summary
    cd16442
    Location:458 → 638
    BPL; biotin protein ligase
    pfam02237
    Location:660 → 707
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:189 → 451
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  2. XM_027415647.2 → XP_027271448.1  biotin--protein ligase isoform X5

    UniProtKB/TrEMBL
    A0A8C2MKE1
    Conserved Domains (3) summary
    cd16442
    Location:458 → 638
    BPL; biotin protein ligase
    pfam02237
    Location:660 → 707
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:189 → 451
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  3. XM_027415645.2 → XP_027271446.1  biotin--protein ligase isoform X2

    UniProtKB/TrEMBL
    A0A9J7G0N3
    Related
    ENSCGRP00015019723.1, ENSCGRT00015024306.2
    Conserved Domains (3) summary
    cd16442
    Location:605 → 785
    BPL; biotin protein ligase
    pfam02237
    Location:807 → 854
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:336 → 598
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  4. XM_035444285.1 → XP_035300176.1  biotin--protein ligase isoform X4

    UniProtKB/TrEMBL
    A0A9J7GWE3
    Conserved Domains (3) summary
    cd16442
    Location:566 → 746
    BPL; biotin protein ligase
    pfam02237
    Location:768 → 815
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:415 → 559
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  5. XM_027415646.2 → XP_027271447.1  biotin--protein ligase isoform X3

    UniProtKB/TrEMBL
    A0A9J7FYR5

  6. XM_035444287.1 → XP_035300178.1  biotin--protein ligase isoform X6

    UniProtKB/TrEMBL
    A0A9J7H0M1
    Conserved Domains (1) summary
    cl00020
    Location:336 → 598
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  7. XM_035444286.1 → XP_035300177.1  biotin--protein ligase isoform X5

    UniProtKB/TrEMBL
    A0A8C2MKE1
    Conserved Domains (3) summary
    cd16442
    Location:458 → 638
    BPL; biotin protein ligase
    pfam02237
    Location:660 → 707
    BPL_C; Biotin protein ligase C terminal domain
    cl00020
    Location:189 → 451
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain
Nucleotide Protein Strain
Heading Accession and Version

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