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Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100750895, updated on 8-Mar-2024

Summary

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Gene symbol
Atic
Gene description
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
See related
Ensembl:ENSCGRG00015028921
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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See Atic in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614675.1 (310377..334040, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 2 NC_048595.1 (424939408..424963372)

NW_003614675.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107979147 Neighboring gene fibronectin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IMP cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional purine biosynthesis protein ATIC
Names
Bifunctional purine biosynthesis protein PURH

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614675.1 Reference CriGri_1.0 Primary Assembly

    Range
    310377..334040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007649845.4 → XP_007648035.1  bifunctional purine biosynthesis protein ATIC

    See identical proteins and their annotated locations for XP_007648035.1

    UniProtKB/TrEMBL
    G3I1V4
    Conserved Domains (3) summary
    PRK07106
    Location:203 → 592
    PRK07106; 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; Provisional
    COG0138
    Location:7 → 592
    PurH; AICAR transformylase/IMP cyclohydrolase PurH [Nucleotide transport and metabolism]
    cd01421
    Location:5 → 193
    IMPCH; Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates ...

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048595.1 Alternate CriGri-PICRH-1.0

    Range
    424939408..424963372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027397155.2 → XP_027252956.1  bifunctional purine biosynthesis protein ATIC

    UniProtKB/TrEMBL
    G3I1V4
    Related
    ENSCGRP00015038706.1, ENSCGRT00015047129.2
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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