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Rfwd3 ring finger and WD repeat domain 3 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100716272, updated on 8-Mar-2024
Gene symbol
Rfwd3
Gene description
ring finger and WD repeat domain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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See Rfwd3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947487.1 (106241955..106276127, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176397.1 (2691872..2726086)

NW_026947487.1Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase phosphatase regulatory subunit Neighboring gene golgi glycoprotein 1 Neighboring gene 5S ribosomal RNA Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene mixed lineage kinase domain like pseudokinase Neighboring gene fatty acid 2-hydroxylase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase RFWD3

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947487.1 Reference mCavPor4.1

    Range
    106241955..106276127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005004607.4 → XP_005004664.1  E3 ubiquitin-protein ligase RFWD3 isoform X2

    UniProtKB/TrEMBL
    H0UUW2
    Conserved Domains (4) summary
    COG2319
    Location:657 → 750
    WD40; WD40 repeat [General function prediction only]
    cd00162
    Location:460 → 506
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00039
    Location:672 → 708
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:667 → 943
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_063247661.1 → XP_063103731.1  E3 ubiquitin-protein ligase RFWD3 isoform X3

  3. XM_005004606.4 → XP_005004663.1  E3 ubiquitin-protein ligase RFWD3 isoform X1

    UniProtKB/TrEMBL
    H0UUW2
    Conserved Domains (4) summary
    COG2319
    Location:658 → 751
    WD40; WD40 repeat [General function prediction only]
    cd00162
    Location:461 → 507
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00039
    Location:673 → 709
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:668 → 944
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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