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Smoc1 SPARC related modular calcium binding 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100714493, updated on 3-Dec-2024

Summary

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Gene symbol
Smoc1
Gene description
SPARC related modular calcium binding 1
See related
Ensembl:ENSCPOG00000008973
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Smoc1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947514.1 (31651765..31799998, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176399.1 (14472850..14619063)

NW_026947514.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134474155 Neighboring gene solute carrier family 8 member A3 Neighboring gene prostaglandin E synthase 3-like Neighboring gene solute carrier family 10 member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables extracellular matrix binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SPARC-related modular calcium-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947514.1 Reference mCavPor4.1

    Range
    31651765..31799998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013155262.2 → XP_013010716.1  SPARC-related modular calcium-binding protein 1 isoform X5

    UniProtKB/TrEMBL
    H0VDK4
    Conserved Domains (5) summary
    smart00280
    Location:42 → 87
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:237 → 303
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:375 → 436
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam00086
    Location:95 → 158
    Thyroglobulin_1; Thyroglobulin type-1 repeat
    pfam16597
    Location:159 → 228
    Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

  2. XM_063241320.1 → XP_063097390.1  SPARC-related modular calcium-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    H0VDK4

  3. XM_013155259.2 → XP_013010713.1  SPARC-related modular calcium-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    H0VDK4
    Conserved Domains (5) summary
    smart00280
    Location:42 → 87
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:237 → 303
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:375 → 436
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam00086
    Location:95 → 158
    Thyroglobulin_1; Thyroglobulin type-1 repeat
    pfam16597
    Location:159 → 228
    Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

  4. XM_013155260.2 → XP_013010714.1  SPARC-related modular calcium-binding protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A286XXC6, H0VDK4
    Related
    ENSCPOP00000030193.1
    Conserved Domains (5) summary
    smart00280
    Location:42 → 87
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:226 → 292
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:364 → 425
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam00086
    Location:95 → 158
    Thyroglobulin_1; Thyroglobulin type-1 repeat
    pfam16597
    Location:159 → 217
    Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

  5. XM_013155261.2 → XP_013010715.1  SPARC-related modular calcium-binding protein 1 isoform X4

    UniProtKB/TrEMBL
    H0VDK4
    Related
    ENSCPOP00000008062.3
    Conserved Domains (5) summary
    smart00280
    Location:42 → 87
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:237 → 303
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:375 → 436
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam00086
    Location:95 → 158
    Thyroglobulin_1; Thyroglobulin type-1 repeat
    pfam16597
    Location:159 → 228
    Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

  6. XM_013155263.3 → XP_013010717.1  SPARC-related modular calcium-binding protein 1 isoform X6

    UniProtKB/TrEMBL
    H0VDK4
    Conserved Domains (5) summary
    smart00280
    Location:16 → 61
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:211 → 277
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:349 → 410
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam00086
    Location:69 → 132
    Thyroglobulin_1; Thyroglobulin type-1 repeat
    pfam16597
    Location:133 → 202
    Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain
Nucleotide Protein
Heading Accession and Version

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