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Dld dihydrolipoamide dehydrogenase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100689437, updated on 19-Feb-2025

Summary

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Gene symbol
Dld
Gene description
dihydrolipoamide dehydrogenase
See related
Ensembl:ENSCGRG00015004692
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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See Dld in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614696.1 (251738..273630)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 5 NC_048598.1 (168833126..168854166, complement)

NW_003614696.1Genomic Context describing neighboring genes Neighboring gene Cbl proto-oncogene like 1 Neighboring gene solute carrier family 26 member 3 Neighboring gene laminin subunit beta 1 Neighboring gene 40S ribosomal protein S7-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydrolipoyl dehydrogenase (NADH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydrolipoyl dehydrogenase, mitochondrial
NP_001233626.1
XP_007648126.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246697.1 → NP_001233626.1  dihydrolipoyl dehydrogenase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001233626.1

    Status: PROVISIONAL

    Source sequence(s)
    AF539836
    UniProtKB/Swiss-Prot
    Q8CIZ7
    UniProtKB/TrEMBL
    A0A061I3V4
    Related
    ENSCGRP00015006108.2, ENSCGRT00015007543.2
    Conserved Domains (4) summary
    PRK06327
    Location:43 → 509
    PRK06327; dihydrolipoamide dehydrogenase; Validated
    pfam00070
    Location:215 → 288
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam02852
    Location:390 → 496
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
    pfam13450
    Location:46 → 80
    NAD_binding_8; NAD(P)-binding Rossmann-like domain

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614696.1 Reference CriGri_1.0 Primary Assembly

    Range
    251738..273630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007649936.4 → XP_007648126.1  dihydrolipoyl dehydrogenase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_007648126.1

    UniProtKB/TrEMBL
    A0A061I3V4, G3I277
    Conserved Domains (4) summary
    PRK06327
    Location:43 → 509
    PRK06327; dihydrolipoamide dehydrogenase; Validated
    pfam00070
    Location:215 → 288
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam02852
    Location:390 → 496
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
    cl21454
    Location:45 → 222
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048598.1 Alternate CriGri-PICRH-1.0

    Range
    168833126..168854166 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CIZ7.1 GenPept UniProtKB/Swiss-Prot:Q8CIZ7

Gene LinkOut

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