Sptlc1 serine palmitoyltransferase long chain base subunit 1 [Cricetulus griseus (Chinese hamster)] - Gene

Summary

Gene symbol: Sptlc1
Gene description: serine palmitoyltransferase long chain base subunit 1
See related: Ensembl:ENSCGRG00015019207
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Cricetulus griseus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as: LCB1; SPT1
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
104	current	CriGri_1.0 (GCF_000223135.1)	Unplaced Scaffold	NW_003614498.1 (47528..87661)
104	current	CriGri-PICRH-1.0 (GCF_003668045.3)	3	NC_048596.1 (272274891..272315062, complement)

NW_003614498.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine C-palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in ceramide biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sphingosine biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine palmitoyltransferase 1

Names: LCB 1; Long chain base biosynthesis protein 1; SPT 1; Serine-palmitoyl-CoA transferase 1; serine palmitoyltransferase LCB1 subunit

NP_001233688.1

EC 2.3.1.50

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001246759.1 → NP_001233688.1 serine palmitoyltransferase 1

See identical proteins and their annotated locations for NP_001233688.1

Status: PROVISIONAL

Source sequence(s)

AF004831

UniProtKB/Swiss-Prot

O54695

Related

ENSCGRP00015025332.2, ENSCGRT00015031065.2

Conserved Domains (2) summary

COG0156
Location:81 → 467

BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]

cl18945
Location:11 → 472

AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...