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DENND3 DENN domain containing 3 [ Canis lupus familiaris (dog) ]

Gene ID: 100688774, updated on 8-Mar-2024

Summary

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Official Symbol
DENND3provided by VGNC
Official Full Name
DENN domain containing 3provided by VGNC
Primary source
VGNC:VGNC:39889
See related
Ensembl:ENSCAFG00845012933
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (36031571..36081695)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (35505304..35555435)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (36261339..36311719)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (35751650..35801765)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (35841295..35891529)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098577 Neighboring gene uncharacterized LOC106559645 Neighboring gene solute carrier family 45 member 4 Neighboring gene uncharacterized LOC119874438

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DENN domain-containing protein 3
Names
DENN/MADD domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    36031571..36081695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685138.1 → XP_038541066.1  DENN domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFY7
    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1038 → 1282
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038685139.1 → XP_038541067.1  DENN domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QFY7
    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    COG2319
    Location:987 → 1283
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain

  3. XM_038685140.1 → XP_038541068.1  DENN domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QFY7, A0A8I3NYM4
    Related
    ENSCAFP00845018041.1, ENSCAFT00845023012.1
    Conserved Domains (5) summary
    smart00801
    Location:430 → 492
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1064 → 1101
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 368
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1023 → 1267
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_005436572.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    35751650..35801765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493380.1 → XP_038349308.1  DENN domain-containing protein 3 isoform X1

    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1038 → 1282
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038493381.1 → XP_038349309.1  DENN domain-containing protein 3 isoform X2

    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    COG2319
    Location:987 → 1283
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain

  3. XM_038493382.1 → XP_038349310.1  DENN domain-containing protein 3 isoform X3

    Conserved Domains (5) summary
    smart00801
    Location:430 → 492
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1064 → 1101
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 368
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1023 → 1267
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_005335082.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    35841295..35891529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619532.1 → XP_038475460.1  DENN domain-containing protein 3 isoform X1

    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1038 → 1282
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038619533.1 → XP_038475461.1  DENN domain-containing protein 3 isoform X2

    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    COG2319
    Location:987 → 1283
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain

  3. XM_038619534.1 → XP_038475462.1  DENN domain-containing protein 3 isoform X3

    Conserved Domains (5) summary
    smart00801
    Location:430 → 492
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1064 → 1101
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 368
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1023 → 1267
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_005403132.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    36261339..36311719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555631.1 → XP_038411559.1  DENN domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFY7

  2. XM_038555632.1 → XP_038411560.1  DENN domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QFY7

  3. XM_038555633.1 → XP_038411561.1  DENN domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QFY7

RNA

  1. XR_005368835.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35505304..35555435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424614.1 → XP_038280542.1  DENN domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QFY7
    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1038 → 1282
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038424627.1 → XP_038280555.1  DENN domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QFY7
    Conserved Domains (5) summary
    smart00801
    Location:445 → 507
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    COG2319
    Location:987 → 1283
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1079 → 1116
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 383
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain

  3. XM_038424636.1 → XP_038280564.1  DENN domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L160, A0A8C0QFY7, A0A8P0PQ53
    Conserved Domains (5) summary
    smart00801
    Location:430 → 492
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    sd00039
    Location:1064 → 1101
    7WD40; WD40 repeat [structural motif]
    pfam02141
    Location:182 → 368
    DENN; DENN (AEX-3) domain
    cl04085
    Location:112 → 148
    uDENN; uDENN domain
    cl29593
    Location:1023 → 1267
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_005296549.1 RNA Sequence

Nucleotide Protein
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