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RGS7 regulator of G protein signaling 7 [ Canis lupus familiaris (dog) ]

Gene ID: 100687600, updated on 27-Jun-2026
Official Symbol
RGS7provided by VGNC
Official Full Name
regulator of G protein signaling 7provided by VGNC
Primary source
VGNC:VGNC:45536
See related
Ensembl:ENSCAFG00845004226 RGD:12160554
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See RGS7 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (32121410..32620141, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (31844360..32355859, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (32231779..32720515, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (31959165..32454995, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (31990446..32479343, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC119872537 Neighboring gene uncharacterized LOC119872536 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene uncharacterized LOC102155155 Neighboring gene uncharacterized LOC111096678 Neighboring gene uncharacterized LOC119872538 Neighboring gene ribosome biogenesis protein NSA2 homolog Neighboring gene uncharacterized LOC106559037 Neighboring gene fumarate hydratase Neighboring gene kynurenine 3-monooxygenase Neighboring gene opsin 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
regulator of G-protein signaling 7

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    32121410..32620141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671498.1 → XP_038527426.1  regulator of G-protein signaling 7 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MPW5, A0A8I3MS14
    Related
    ENSCAFP00845006163.1, ENSCAFT00845007781.1
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  2. XM_038671497.1 → XP_038527425.1  regulator of G-protein signaling 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LEZ8, A0A8I3MKN3
    Related
    ENSCAFP00845006149.1, ENSCAFT00845007766.1
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  3. XM_038671496.1 → XP_038527424.1  regulator of G-protein signaling 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LGP5, A0A8I3RRZ5
    Related
    ENSCAFP00845006159.1, ENSCAFT00845007777.1
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  4. XM_038671499.1 → XP_038527427.1  regulator of G-protein signaling 7 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LJX9
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    31959165..32454995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481315.1 → XP_038337243.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  2. XM_038481314.1 → XP_038337242.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  3. XM_038481313.1 → XP_038337241.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  4. XM_038481316.1 → XP_038337244.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    31990446..32479343 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606820.1 → XP_038462748.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  2. XM_038606819.1 → XP_038462747.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  3. XM_038606818.1 → XP_038462746.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  4. XM_038606821.1 → XP_038462749.1  

    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    32231779..32720515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542673.1 → XP_038398601.1  regulator of G-protein signaling 7 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MPW5, A0A8I3MS14
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  2. XM_038542672.1 → XP_038398600.1  regulator of G-protein signaling 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LEZ8, A0A8I3MKN3
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  3. XM_038542671.1 → XP_038398599.1  regulator of G-protein signaling 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LGP5
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  4. XM_038542674.1 → XP_038398602.1  regulator of G-protein signaling 7 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LJX9
    Conserved Domains (4) summary
    smart00224
    Location:256 → 316
    GGL; G protein gamma subunit-like motifs
    cd08738
    Location:326 → 446
    RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 214
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    31844360..32355859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567970.1 → XP_038423898.1  regulator of G-protein signaling 7 isoform X5

    Conserved Domains (2) summary
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 204
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  2. XM_038567997.1 → XP_038423925.1  regulator of G-protein signaling 7 isoform X6

    Conserved Domains (2) summary
    cd04450
    Location:18 → 105
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:102 → 193
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  3. XM_038567988.1 → XP_038423916.1  regulator of G-protein signaling 7 isoform X6

    Conserved Domains (2) summary
    cd04450
    Location:18 → 105
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:102 → 193
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  4. XM_038567962.1 → XP_038423890.1  regulator of G-protein signaling 7 isoform X5

    Conserved Domains (2) summary
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 204
    RGS_DHEX; Regulator of G-protein signalling DHEX domain

  5. XM_038567978.1 → XP_038423906.1  regulator of G-protein signaling 7 isoform X5

    Conserved Domains (2) summary
    cd04450
    Location:29 → 116
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    pfam18148
    Location:113 → 204
    RGS_DHEX; Regulator of G-protein signalling DHEX domain
Nucleotide Protein
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