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LAMA2 laminin subunit alpha 2 [ Canis lupus familiaris (dog) ]

Gene ID: 100683420, updated on 25-Jul-2026
Official Symbol
LAMA2provided by VGNC
Official Full Name
laminin subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:42565
See related
Ensembl:ENSCAFG00845001120 RGD:12353097
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See LAMA2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
65
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (67721690..68305337)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (68254521..68844637)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (68070825..68654877)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (67644723..68228165)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (67427961..68011313)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene uncharacterized LOC106558822 Neighboring gene pre-mRNA-splicing regulator WTAP-like Neighboring gene THO complex subunit 6 homolog Neighboring gene uncharacterized LOC119870797 Neighboring gene uncharacterized LOC119870796 Neighboring gene uncharacterized LOC119875969 Neighboring gene non-histone chromosomal protein HMG-17-like Neighboring gene uncharacterized LOC111096277

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
laminin subunit alpha-2
Names
laminin alpha 2 subunit
laminin, alpha 2 (merosin, congenital muscular dystrophy)
XP_038322000.1

Length

  • 3119

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    67721690..68305337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038654855.1 → XP_038510783.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RRA4
    Related
    ENSCAFP00845001534.1, ENSCAFT00845001954.1
    Conserved Domains (11) summary
    smart00180
    Location:964 → 1008
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1226 → 1361
    LamB; Laminin B domain
    cd00055
    Location:914 → 962
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2938 → 3090
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1732 → 2092
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1591 → 1849
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2034 → 2170
    Laminin_II; Laminin Domain II
    pfam00052
    Location:580 → 719
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1057 → 1105
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2790 → 2918
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:37 → 282
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_038654856.1 → XP_038510784.1  laminin subunit alpha-2 isoform X2

    Conserved Domains (11) summary
    smart00180
    Location:964 → 1008
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1226 → 1361
    LamB; Laminin B domain
    cd00055
    Location:914 → 962
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2934 → 3086
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1732 → 2092
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1591 → 1849
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2034 → 2170
    Laminin_II; Laminin Domain II
    pfam00052
    Location:580 → 719
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1057 → 1105
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2786 → 2914
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:37 → 282
    Laminin_N; Laminin N-terminal (Domain VI)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    67644723..68228165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038466072.1 → XP_038322000.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    67427961..68011313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038591057.1 → XP_038446985.1  

  2. XM_038591055.1 → XP_038446983.1  

  3. XM_038591058.1 → XP_038446986.1  

  4. XM_038591056.1 → XP_038446984.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    68070825..68654877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038526758.1 → XP_038382686.1  laminin subunit alpha-2 isoform X1

  2. XM_038526759.1 → XP_038382687.1  laminin subunit alpha-2 isoform X2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    68254521..68844637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554961.1 → XP_038410889.1  laminin subunit alpha-2 isoform X1

    Conserved Domains (11) summary
    smart00180
    Location:964 → 1008
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1226 → 1361
    LamB; Laminin B domain
    cd00055
    Location:914 → 962
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2938 → 3090
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1732 → 2092
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1591 → 1849
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2034 → 2170
    Laminin_II; Laminin Domain II
    pfam00052
    Location:580 → 719
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1057 → 1105
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2790 → 2918
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:37 → 282
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_038555021.1 → XP_038410949.1  laminin subunit alpha-2 isoform X2

    Conserved Domains (11) summary
    smart00180
    Location:964 → 1008
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1226 → 1361
    LamB; Laminin B domain
    cd00055
    Location:914 → 962
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2934 → 3086
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1732 → 2092
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1591 → 1849
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2034 → 2170
    Laminin_II; Laminin Domain II
    pfam00052
    Location:580 → 719
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1057 → 1105
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2786 → 2914
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:37 → 282
    Laminin_N; Laminin N-terminal (Domain VI)
Nucleotide Protein
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