U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

IQSEC1 IQ motif and Sec7 domain ArfGEF 1 [ Canis lupus familiaris (dog) ]

Gene ID: 100683208, updated on 25-Jul-2026
Official Symbol
IQSEC1provided by VGNC
Official Full Name
IQ motif and Sec7 domain ArfGEF 1provided by VGNC
Primary source
VGNC:VGNC:42083
See related
Ensembl:ENSCAFG00845021688 RGD:12267283
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See IQSEC1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (3257657..3635203, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (3275721..3653100, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (3264034..3641876, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (2976955..3354374, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (3299223..3676904, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 92 (putative) Neighboring gene uncharacterized LOC119864624 Neighboring gene acyl-CoA dehydrogenase family member 9 Neighboring gene uncharacterized LOC119864625 Neighboring gene uncharacterized LOC119864626 Neighboring gene nucleoporin 210 Neighboring gene uncharacterized LOC100687984

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
IQ motif and SEC7 domain-containing protein 1
Names
IQ motif and Sec7 domain 1
XP_038358531.1

Length

  • 1232
XP_038421443.1

Length

  • 1233

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    3257657..3635203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426796.1 → XP_038282724.1  IQ motif and SEC7 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:626 → 814
    Sec7; Sec7 domain
    pfam16453
    Location:846 → 981
    IQ_SEC7_PH; PH domain

  2. XM_038426802.1 → XP_038282730.1  IQ motif and SEC7 domain-containing protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  3. XM_038426804.1 → XP_038282732.1  IQ motif and SEC7 domain-containing protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  4. XM_038426805.1 → XP_038282733.1  IQ motif and SEC7 domain-containing protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  5. XM_038426806.1 → XP_038282734.1  IQ motif and SEC7 domain-containing protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A8I3P8P1, A0A8I3PMF4
    Related
    ENSCAFP00845029974.1, ENSCAFT00845038271.1
    Conserved Domains (2) summary
    pfam01369
    Location:524 → 712
    Sec7; Sec7 domain
    pfam16453
    Location:744 → 879
    IQ_SEC7_PH; PH domain

  6. XM_038426801.1 → XP_038282729.1  IQ motif and SEC7 domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3PB44, A0A8I3PMF4
    Related
    ENSCAFP00845030850.1, ENSCAFT00845039373.1
    Conserved Domains (2) summary
    pfam01369
    Location:510 → 698
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 865
    IQ_SEC7_PH; PH domain

  7. XM_038426798.1 → XP_038282726.1  IQ motif and SEC7 domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PGF5, A0A8I3PMF4
    Related
    ENSCAFP00845030059.1, ENSCAFT00845038389.1
    Conserved Domains (2) summary
    pfam01369
    Location:528 → 716
    Sec7; Sec7 domain
    pfam16453
    Location:748 → 883
    IQ_SEC7_PH; PH domain

  8. XM_038426799.1 → XP_038282727.1  IQ motif and SEC7 domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3P944, A0A8I3PMF4
    Related
    ENSCAFP00845030167.1, ENSCAFT00845038529.1
    Conserved Domains (2) summary
    pfam01369
    Location:525 → 713
    Sec7; Sec7 domain
    pfam16453
    Location:745 → 880
    IQ_SEC7_PH; PH domain

  9. XM_038426807.1 → XP_038282735.1  IQ motif and SEC7 domain-containing protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:402 → 590
    Sec7; Sec7 domain
    pfam16453
    Location:622 → 757
    IQ_SEC7_PH; PH domain

  10. XM_038426797.1 → XP_038282725.1  IQ motif and SEC7 domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PAC3, A0A8I3PMF4
    Related
    ENSCAFP00845030547.1, ENSCAFT00845038998.1
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  11. XM_038426800.1 → XP_038282728.1  IQ motif and SEC7 domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0JW40, A0A8I3PEK7, A0A8I3PMF4
    Related
    ENSCAFP00845030634.1, ENSCAFT00845039116.1
    Conserved Domains (2) summary
    pfam01369
    Location:524 → 712
    Sec7; Sec7 domain
    pfam16453
    Location:744 → 879
    IQ_SEC7_PH; PH domain

  12. XM_038426803.1 → XP_038282731.1  IQ motif and SEC7 domain-containing protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

RNA

  1. XR_005297561.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    2976955..3354374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502603.1 → XP_038358531.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    3299223..3676904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038629635.1 → XP_038485563.1  

  2. XM_038629642.1 → XP_038485570.1  

  3. XM_038629644.1 → XP_038485572.1  

  4. XM_038629645.1 → XP_038485573.1  

  5. XM_038629646.1 → XP_038485574.1  

  6. XM_038629641.1 → XP_038485569.1  

  7. XM_038629637.1 → XP_038485565.1  

  8. XM_038629639.1 → XP_038485567.1  

  9. XM_038629647.1 → XP_038485575.1  

  10. XM_038629636.1 → XP_038485564.1  

  11. XM_038629640.1 → XP_038485568.1  

  12. XM_038629643.1 → XP_038485571.1  

RNA

  1. XR_005408540.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    3264034..3641876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038565515.1 → XP_038421443.1  IQ motif and SEC7 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PMF4

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    3275721..3653100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455292.1 → XP_038311220.1  IQ motif and SEC7 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:625 → 813
    Sec7; Sec7 domain
    pfam16453
    Location:845 → 980
    IQ_SEC7_PH; PH domain

  2. XM_038455298.1 → XP_038311226.1  IQ motif and SEC7 domain-containing protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  3. XM_038455300.1 → XP_038311228.1  IQ motif and SEC7 domain-containing protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  4. XM_038455301.1 → XP_038311229.1  IQ motif and SEC7 domain-containing protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  5. XM_038455302.1 → XP_038311230.1  IQ motif and SEC7 domain-containing protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A8I3P8P1, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:524 → 712
    Sec7; Sec7 domain
    pfam16453
    Location:744 → 879
    IQ_SEC7_PH; PH domain

  6. XM_038455297.1 → XP_038311225.1  IQ motif and SEC7 domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3PB44, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:510 → 698
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 865
    IQ_SEC7_PH; PH domain

  7. XM_038455294.1 → XP_038311222.1  IQ motif and SEC7 domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PGF5, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:528 → 716
    Sec7; Sec7 domain
    pfam16453
    Location:748 → 883
    IQ_SEC7_PH; PH domain

  8. XM_038455295.1 → XP_038311223.1  IQ motif and SEC7 domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3P944, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:525 → 713
    Sec7; Sec7 domain
    pfam16453
    Location:745 → 880
    IQ_SEC7_PH; PH domain

  9. XM_038455303.1 → XP_038311231.1  IQ motif and SEC7 domain-containing protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:402 → 590
    Sec7; Sec7 domain
    pfam16453
    Location:622 → 757
    IQ_SEC7_PH; PH domain

  10. XM_038455293.1 → XP_038311221.1  IQ motif and SEC7 domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PAC3, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

  11. XM_038455296.1 → XP_038311224.1  IQ motif and SEC7 domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0JW40, A0A8I3PEK7, A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:524 → 712
    Sec7; Sec7 domain
    pfam16453
    Location:744 → 879
    IQ_SEC7_PH; PH domain

  12. XM_038455299.1 → XP_038311227.1  IQ motif and SEC7 domain-containing protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8I3PMF4
    Conserved Domains (2) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:768 → 903
    IQ_SEC7_PH; PH domain

RNA

  1. XR_005312553.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials