N4bp2l1 NEDD4 binding protein 2-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: N4bp2l1provided by MGI
Official Full Name: NEDD4 binding protein 2-like 1provided by MGI
Primary source: MGI:MGI:2140872
See related: Ensembl:ENSMUSG00000041132 AllianceGenome:MGI:2140872
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2410024N18Rik; B230342M21Rik
Summary: Orthologous to human N4BP2L1 (NEDD4 binding protein 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in frontal lobe adult (RPKM 8.5), cortex adult (RPKM 8.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 5; 5 G3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (150495108..150518288, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (150571643..150598678, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

BE685977 (e-PCR)
- UniSTS:207918

AI428195 (e-PCR)
- UniSTS:159477

Homology

Homologs of the N4bp2l1 gene: The N4bp2l1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, rat, chicken, and frog.
Orthologs from Annotation Pipeline: 336 organisms have orthologs with human gene N4bp2l1
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: NEDD4-binding protein 2-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_133898.4 → NP_598659.3 NEDD4-binding protein 2-like 1

See identical proteins and their annotated locations for NP_598659.3

Status: VALIDATED

Source sequence(s)

AK131647, BB629746, BE447039

Consensus CDS

CCDS19887.1

UniProtKB/Swiss-Prot

Q3V2Q8, Q8VE50

Related

ENSMUSP00000016279.8, ENSMUST00000016279.11

Conserved Domains (2) summary

pfam13671
Location:42 → 175

AAA_33; AAA domain

cl17190
Location:42 → 175

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...