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MIR3976 microRNA 3976 [ Homo sapiens (human) ]

Gene ID: 100616244, updated on 23-Nov-2021

Summary

Official Symbol
MIR3976provided by HGNC
Official Full Name
microRNA 3976provided by HGNC
Primary source
HGNC:HGNC:41578
See related
Ensembl:ENSG00000272380 miRBase:MI0016994
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR3976 in Genome Data Viewer
Location:
18p11.31
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (5840695..5840833)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (5840694..5840832)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene erythrocyte membrane protein band 4.1 like 3 Neighboring gene uncharacterized LOC107985145 Neighboring gene atrophin-domain containing Neighboring gene MIR3976 host gene Neighboring gene uncharacterized LOC121725015 Neighboring gene transmembrane protein 200C Neighboring gene L3MBTL histone methyl-lysine binding protein 4 Neighboring gene RNA, U5F small nuclear 3, pseudogene

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039772.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP005433
    Related
    ENST00000606807.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

    Range
    5840695..5840833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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