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STAT2 signal transducer and activator of transcription 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100585171, updated on 11-Apr-2024

Summary

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Gene symbol
STAT2
Gene description
signal transducer and activator of transcription 2
See related
EnsemblRapid:ENSNLEG00000017494
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 11 NC_044391.1 (54910804..54930541)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 11 NC_019826.1 (56439794..56473784)

Chromosome 11 - NC_044391.1Genomic Context describing neighboring genes Neighboring gene timeless circadian regulator Neighboring gene U7 small nuclear RNA Neighboring gene apolipoprotein F Neighboring gene interleukin 23 subunit alpha Neighboring gene poly(A) specific ribonuclease subunit PAN2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in type I interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044391.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    54910804..54930541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003252812.2 → XP_003252860.1  signal transducer and activator of transcription 2 isoform X1

    UniProtKB/TrEMBL
    A0A2I3G1P6, G1S6V0
    Related
    ENSNLEP00000021239.1, ENSNLET00000022315.3
    Conserved Domains (5) summary
    cd10373
    Location:556 → 706
    SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
    smart00964
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cd16852
    Location:141 → 312
    STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
    cl28920
    Location:316 → 475
    STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
    pfam12188
    Location:786 → 838
    STAT2_C; Signal transducer and activator of transcription 2 C terminal

  2. XM_030822431.1 → XP_030678291.1  signal transducer and activator of transcription 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3G1P6
    Conserved Domains (5) summary
    cd10373
    Location:549 → 699
    SH2_STAT2; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 2 proteins
    smart00964
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cd16852
    Location:141 → 312
    STAT2_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 2 (STAT2)
    cl28920
    Location:316 → 468
    STAT_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription (STAT)
    pfam12188
    Location:779 → 831
    STAT2_C; Signal transducer and activator of transcription 2 C terminal
Nucleotide Protein
Heading Accession and Version

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