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LRRK2 leucine rich repeat kinase 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100582066, updated on 8-Mar-2024

Summary

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Gene symbol
LRRK2
Gene description
leucine rich repeat kinase 2
See related
EnsemblRapid:ENSNLEG00000017957
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
51
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 11 NC_044391.1 (60968574..61110897)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 11 NC_019826.1 (63712330..63854631)

Chromosome 11 - NC_044391.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 13 Neighboring gene 60S ribosomal protein L30-like Neighboring gene uncharacterized LOC115837367 Neighboring gene mucin 19, oligomeric Neighboring gene U6 spliceosomal RNA Neighboring gene methionine aminopeptidase 1 pseudogene Neighboring gene contactin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat serine/threonine-protein kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044391.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    60968574..61110897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003252300.3 → XP_003252348.1  leucine-rich repeat serine/threonine-protein kinase 2

    UniProtKB/TrEMBL
    G1S8H6
    Related
    ENSNLEP00000021815.2, ENSNLET00000022916.4
    Conserved Domains (6) summary
    PRK15370
    Location:982 → 1200
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    cd09914
    Location:1334 → 1507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    COG4886
    Location:1108 → 1360
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14068
    Location:1884 → 2135
    STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
    sd00033
    Location:1013 → 1036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:1527 → 1740
    COR; C-terminal of Roc, COR, domain
Nucleotide Protein
Heading Accession and Version

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