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setd2 SET domain containing 2, histone lysine methyltransferase [ Anolis carolinensis (green anole) ]

Gene ID: 100559621, updated on 8-Mar-2024

Summary

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Gene symbol
setd2
Gene description
SET domain containing 2, histone lysine methyltransferase
See related
Ensembl:ENSACAG00000002296
Gene type
protein coding
RefSeq status
MODEL
Organism
Anolis carolinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Dactyloidae; Anolis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current rAnoCar3.1.pri (GCF_035594765.1) 6 NC_085846.1 (116990585..117093203, complement)
102 previous assembly AnoCar2.0 (GCF_000090745.1) Unplaced Scaffold NW_003339466.1 (10153..112373)

Chromosome 6 - NC_085846.1Genomic Context describing neighboring genes Neighboring gene neurobeachin like 2 Neighboring gene uncharacterized LOC134292538 Neighboring gene D-serine dehydratase Neighboring gene tumor necrosis factor receptor superfamily member 16 Neighboring gene uncharacterized LOC100553684 Neighboring gene uncharacterized LOC134292540 Neighboring gene kinesin family member 9 Neighboring gene kelch like family member 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K36 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase SETD2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_035594765.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAnoCar3.1.pri

Genomic

  1. NC_085846.1 Reference rAnoCar3.1.pri

    Range
    116990585..117093203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008123477.3 → XP_008121684.1  histone-lysine N-methyltransferase SETD2 isoform X3

    UniProtKB/TrEMBL
    H9G639
    Conserved Domains (7) summary
    smart00570
    Location:1560 → 1614
    AWS; associated with SET domains
    smart00317
    Location:1615 → 1738
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:1739 → 1755
    PostSET; Cysteine-rich motif following a subset of SET domains
    pfam00397
    Location:2453 → 2482
    WW; WW domain
    pfam08236
    Location:2531 → 2610
    SRI; SRI (Set2 Rpb1 interacting) domain
    pfam08648
    Location:460 → 554
    DUF1777; Protein of unknown function (DUF1777)
    pfam14944
    Location:2229 → 2429
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  2. XM_008123476.3 → XP_008121683.1  histone-lysine N-methyltransferase SETD2 isoform X4

    UniProtKB/TrEMBL
    H9G639
    Related
    ENSACAP00000002203.4
    Conserved Domains (7) summary
    smart00570
    Location:1533 → 1587
    AWS; associated with SET domains
    smart00317
    Location:1588 → 1711
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:1712 → 1728
    PostSET; Cysteine-rich motif following a subset of SET domains
    pfam00397
    Location:2426 → 2455
    WW; WW domain
    pfam08236
    Location:2504 → 2583
    SRI; SRI (Set2 Rpb1 interacting) domain
    pfam08648
    Location:433 → 527
    DUF1777; Protein of unknown function (DUF1777)
    pfam14944
    Location:2202 → 2402
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  3. XM_008123475.3 → XP_008121682.1  histone-lysine N-methyltransferase SETD2 isoform X2

    Conserved Domains (7) summary
    smart00570
    Location:1582 → 1636
    AWS; associated with SET domains
    smart00317
    Location:1637 → 1760
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:1761 → 1777
    PostSET; Cysteine-rich motif following a subset of SET domains
    pfam00397
    Location:2474 → 2503
    WW; WW domain
    pfam08236
    Location:2552 → 2631
    SRI; SRI (Set2 Rpb1 interacting) domain
    pfam08648
    Location:482 → 576
    DUF1777; Protein of unknown function (DUF1777)
    pfam14944
    Location:2250 → 2450
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  4. XM_008123474.3 → XP_008121681.1  histone-lysine N-methyltransferase SETD2 isoform X1

    UniProtKB/TrEMBL
    A0A803TT94
    Related
    ENSACAP00000038434.1
    Conserved Domains (7) summary
    smart00570
    Location:1582 → 1636
    AWS; associated with SET domains
    smart00317
    Location:1637 → 1760
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:1761 → 1777
    PostSET; Cysteine-rich motif following a subset of SET domains
    pfam00397
    Location:2475 → 2504
    WW; WW domain
    pfam08236
    Location:2553 → 2632
    SRI; SRI (Set2 Rpb1 interacting) domain
    pfam08648
    Location:482 → 576
    DUF1777; Protein of unknown function (DUF1777)
    pfam14944
    Location:2251 → 2451
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

RNA

  1. XR_001731049.2 RNA Sequence

Nucleotide Protein
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