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mapkap1 MAPK associated protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 100537196, updated on 27-Mar-2024

Summary

Official Symbol
mapkap1provided by ZNC
Official Full Name
MAPK associated protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-041111-178
See related
Ensembl:ENSDARG00000091777 AllianceGenome:ZFIN:ZDB-GENE-041111-178
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7143088; si:ch73-242f23.1
Summary
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Acts upstream of or within cell migration involved in mesendoderm migration and regulation of cell projection assembly. Predicted to be part of TORC2 complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human MAPKAP1 (MAPK associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (5398920..5503951)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (4906751..5011779)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene multivesicular body subunit 12Ba Neighboring gene pre-B-cell leukemia homeobox 3a Neighboring gene apical junction component 1 homolog Neighboring gene RAB, member RAS oncogene family-like 6a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in TORC2 signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell migration involved in mesendoderm migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of cell projection assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of TORC2 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TORC2 complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
target of rapamycin complex 2 subunit MAPKAP1
Names
mitogen-activated protein kinase associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    5398920..5503951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003198574.5XP_003198622.1  target of rapamycin complex 2 subunit MAPKAP1

    UniProtKB/TrEMBL
    A0A8M1RND7, E7EZP2
    Related
    ENSDARP00000111582.2, ENSDART00000124022.3
    Conserved Domains (3) summary
    cd13331
    Location:389496
    PH_Avo1; Avo1 Pleckstrin homology (PH) domain
    pfam05422
    Location:18135
    SIN1; Stress-activated map kinase interacting protein 1 (SIN1)
    pfam16978
    Location:145272
    CRIM; SAPK-interacting protein 1 (Sin1), middle CRIM domain