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NADase NAD glycohydrolase [ Aplysia californica (California sea hare) ]

Gene ID: 100533234, updated on 10-Feb-2026
Gene symbol
NADase
Gene description
NAD glycohydrolase
See related
EnsemblRapid:ENSANYG00000027348
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aplysia californica
Lineage
Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Heterobranchia; Euthyneura; Tectipleura; Aplysiida; Aplysioidea; Aplysiidae; Aplysia
Also known as
ADRC; ADPRC
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See NADase in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
102 current AplCal3.0 (GCF_000002075.1) Unplaced Scaffold NW_004797643.1 (646089..652517, complement)

NW_004797643.1Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase III subunit RPC10 Neighboring gene uncharacterized LOC118478138 Neighboring gene AT-rich interactive domain-containing protein 1B

Genomic Sequence:
NW_004797643 Unplaced Scaffold Reference AplCal3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structure of Aplysia ADP ribosyl cyclase, a homologue of the bifunctional ectozyme CD38. Prasad GS, et al. Nat Struct Biol, 1996 Nov. PMID 8901875
  2. Primary structure of a molluscan egg-specific NADase, a second-messenger enzyme. Glick DL, et al. Cell Regul, 1991 Mar. PMID 1650255, Free PMC Article
  3. Purification and characterization of a molluscan egg-specific NADase, a second-messenger enzyme. Hellmich MR, et al. Cell Regul, 1991 Mar. PMID 1650254, Free PMC Article
  4. Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38. States DJ, et al. Trends Biochem Sci, 1992 Dec. PMID 1471258
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ nucleosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphorus-oxygen lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of B cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Names
2'-phospho-ADP-ribosyl cyclase
2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
2'-phospho-cyclic-ADP-ribose transferase
ADP-ribosyl cyclase
NAD(+) nucleosidase
NP_001191476.1
XP_012940877.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204547.1 → NP_001191476.1  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase precursor

    See identical proteins and their annotated locations for NP_001191476.1

    Status: PROVISIONAL

    Source sequence(s)
    M85206
    UniProtKB/Swiss-Prot
    P29241
    Conserved Domains (1) summary
    cd04759
    Location:28 → 272
    Rib_hydrolase; ADP-ribosyl cyclase, also known as cyclic ADP-ribose hydrolase or CD38

RefSeqs of Annotated Genomes: Aplysia californica Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference AplCal3.0 Primary Assembly

Genomic

  1. NW_004797643.1 Reference AplCal3.0 Primary Assembly

    Range
    646089..652517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013085423.1 → XP_012940877.1  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase isoform X1

    UniProtKB/TrEMBL
    A0ABM1A4V5
    Related
    ENSANYP00000025545.1, ENSANYT00000045561.1
    Conserved Domains (1) summary
    cd04759
    Location:28 → 272
    Rib_hydrolase; ADP-ribosyl cyclase, also known as cyclic ADP-ribose hydrolase or CD38
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P29241.1 GenPept UniProtKB/Swiss-Prot:P29241

Gene LinkOut

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Molecular Biology Databases