Format

Send to:

Choose Destination

HSPE1-MOB4 HSPE1-MOB4 readthrough [ Homo sapiens (human) ]

Gene ID: 100529241, updated on 29-Mar-2018

Summary

Official Symbol
HSPE1-MOB4provided by HGNC
Official Full Name
HSPE1-MOB4 readthroughprovided by HGNC
Primary source
HGNC:HGNC:49184
See related
Ensembl:ENSG00000270757 Vega:OTTHUMG00000184877
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSPE1-PHOCN
Summary
This locus represents naturally occurring read-through transcription between the neighboring HSPE1 (heat shock 10kDa protein 1 (chaperonin 10)) and MOB4 (MOB family member 4, phocein) genes on chromosome 2. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Oct 2011]
Expression
Ubiquitous expression in adrenal (RPKM 42.3), kidney (RPKM 19.1) and 24 other tissues See more
Orthologs

Genomic context

See HSPE1-MOB4 in Genome Data Viewer
Location:
2q33.1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (197499997..197553699)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (198364721..198418423)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene coenzyme Q10B Neighboring gene small nucleolar RNA, H/ACA box 105B Neighboring gene heat shock protein family D (Hsp60) member 1 Neighboring gene heat shock protein family E (Hsp10) member 1 Neighboring gene MOB family member 4, phocein Neighboring gene RNY5 pseudogene 2 Neighboring gene raftlin family member 2 Neighboring gene methionyl-tRNA synthetase 2, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Markers

Readthrough HSPE1-MOB4

Included genes: HSPE1, MOB4

Homology

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001202485.1NP_001189414.1  HSPE1-MOB4 protein

    See identical proteins and their annotated locations for NP_001189414.1

    Status: REVIEWED

    Source sequence(s)
    AC020550
    Consensus CDS
    CCDS63079.1
    UniProtKB/TrEMBL
    S4R3N1
    Related
    ENSP00000474534.1, OTTHUMP00000272921, ENST00000604458.1, OTTHUMT00000469293
    Conserved Domains (2) summary
    cd00320
    Location:857
    cpn10; Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It ...
    pfam03637
    Location:89243
    Mob1_phocein; Mob1/phocein family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    197499997..197553699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center