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CORO7-PAM16 CORO7-PAM16 readthrough [ Homo sapiens (human) ]

Gene ID: 100529144, updated on 13-May-2022

Summary

Official Symbol
CORO7-PAM16provided by HGNC
Official Full Name
CORO7-PAM16 readthroughprovided by HGNC
Primary source
HGNC:HGNC:44424
See related
Ensembl:ENSG00000103426 AllianceGenome:HGNC:44424
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Crn7; CORO7; Coronin-7
Summary
This locus represents naturally occurring read-through transcription between the neighboring CORO7 (coronin 7) and PAM16 (presequence translocase-associated motor 16) genes on chromosome 16. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jan 2011]
Expression
Broad expression in bone marrow (RPKM 21.4), spleen (RPKM 16.2) and 24 other tissues See more
Orthologs
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Genomic context

See CORO7-PAM16 in Genome Data Viewer
Location:
16p13.3
Exon count:
31
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (4340251..4416596, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (4367543..4445792, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (4390252..4466597, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903634 Neighboring gene transcription factor AP-4 Neighboring gene GLIS2 antisense RNA 1 Neighboring gene GLIS family zinc finger 2 Neighboring gene presequence translocase associated motor 16 Neighboring gene coronin 7 Neighboring gene vasorin Neighboring gene uncharacterized LOC124903635 Neighboring gene DnaJ heat shock protein family (Hsp40) member A3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp434B212

General protein information

Preferred Names
CORO7-PAM16 protein
Names
70 kDa WD repeat tumor rejection antigen homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201479.2NP_001188408.1  CORO7-PAM16 protein

    Status: VALIDATED

    Source sequence(s)
    AC012676, BC032732
    UniProtKB/TrEMBL
    A0A0A6YYL4
    Related
    ENSP00000460885.1, ENST00000572467.5
    Conserved Domains (5) summary
    pfam03656
    Location:9251048
    Pam16; Pam16
    pfam08953
    Location:560
    DUF1899; Domain of unknown function (DUF1899)
    pfam16300
    Location:808852
    WD40_4; Type of WD40 repeat
    sd00039
    Location:81124
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:546704
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    4340251..4416596 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187608.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    40615..118919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    4367543..4445792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)