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BLOC1S5-TXNDC5 BLOC1S5-TXNDC5 readthrough (NMD candidate) [ Homo sapiens (human) ]

Gene ID: 100526836, updated on 14-May-2022

Summary

Official Symbol
BLOC1S5-TXNDC5provided by HGNC
Official Full Name
BLOC1S5-TXNDC5 readthrough (NMD candidate)provided by HGNC
Primary source
HGNC:HGNC:42001
See related
Ensembl:ENSG00000259040 AllianceGenome:HGNC:42001
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MUTED-TXNDC5
Summary
This locus represents naturally occurring read-through transcription between the neighboring MUTED (muted homolog) and TXNDC5 (thioredoxin domain containing 5) genes on chromosome 6. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Dec 2010]
Expression
Ubiquitous expression in urinary bladder (RPKM 156.2), colon (RPKM 129.2) and 25 other tissues See more
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Genomic context

See BLOC1S5-TXNDC5 in Genome Data Viewer
Location:
6p24.3
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (7881250..8064414, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (7749999..7933150, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (7881483..8064647, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein L29 pseudogene 1 Neighboring gene uncharacterized LOC105374906 Neighboring gene Sharpr-MPRA regulatory region 4297 Neighboring gene bone morphogenetic protein 6 Neighboring gene thioredoxin domain containing 5 Neighboring gene EEF1E1-BLOC1S5 readthrough (NMD candidate) Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 pseudogene 1 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 5 Neighboring gene small Cajal body-specific RNA 27 Neighboring gene eukaryotic translation elongation factor 1 epsilon 1 Neighboring gene uncharacterized LOC105374910

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genetics of coronary artery calcification among African Americans, a meta-analysis.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • BLOC1S5-TXNDC5 readthrough (non-protein coding)
  • MUTED-TXNDC5 readthrough (non-protein coding)

Clone Names

  • FLJ21789, MGC59718

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037616.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL023694, AL133541, BC052310
    Related
    ENST00000439343.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    7881250..8064414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    7749999..7933150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)