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PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough [ Homo sapiens (human) ]

Gene ID: 100526832, updated on 5-Aug-2018

Summary

Gene symbol
PHOSPHO2-KLHL23
Gene description
PHOSPHO2-KLHL23 readthrough
See related
Ensembl:ENSG00000213160 Vega:OTTHUMG00000132213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus represents naturally occurring read-through transcription between the neighboring PHOSPHO2 (phosphatase, orphan 2) and KLHL23 (kelch-like 23) genes on chromosome 2. The read-through transcript includes only non-coding PHOSPHO2 exons, and thus encodes the KLHL23 protein. [provided by RefSeq, Dec 2010]
Expression
Ubiquitous expression in endometrium (RPKM 11.9), brain (RPKM 7.7) and 22 other tissues See more
Orthologs

Genomic context

See PHOSPHO2-KLHL23 in Genome Data Viewer
Location:
2q31.1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (169694431..169751886)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (170550964..170608396)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase G Neighboring gene coiled-coil domain containing 173 Neighboring gene family with sequence similarity 49 member B pseudogene Neighboring gene phosphatase, orphan 2 Neighboring gene kelch like family member 23 Neighboring gene thioredoxin 1 pseudogene 7 Neighboring gene patched domain containing 3 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ33334

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199290.2NP_001186219.1  kelch-like protein 23

    See identical proteins and their annotated locations for NP_001186219.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the protein.
    Source sequence(s)
    AC009967, AC016772
    UniProtKB/Swiss-Prot
    Q8NBE8
    Related
    ENSP00000272797.4, OTTHUMP00000204783, ENST00000272797.8, OTTHUMT00000333330
    Conserved Domains (2) summary
    sd00038
    Location:359402
    Kelch; KELCH repeat [structural motif]
    cl28614
    Location:45545
    BTB; Broad-Complex, Tramtrack and Bric a brac

RNA

  1. NR_144936.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate internal exon, resulting in a shorter transcript compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AC009967, AC016772

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    169694431..169751886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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