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TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough [ Homo sapiens (human) ]

Gene ID: 100526772, updated on 29-Mar-2018

Summary

Official Symbol
TMEM110-MUSTN1provided by HGNC
Official Full Name
TMEM110-MUSTN1 readthroughprovided by HGNC
Primary source
HGNC:HGNC:38834
See related
Ensembl:ENSG00000248592 Vega:OTTHUMG00000160756
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus represents naturally occurring read-through transcription between the neighboring TMEM110 (transmembrane protein 110) and MUSTN1 (musculoskeletal, embryonic nuclear protein 1) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]
Expression
Ubiquitous expression in lung (RPKM 19.9), prostate (RPKM 19.7) and 25 other tissues See more
Orthologs

Genomic context

See TMEM110-MUSTN1 in Genome Data Viewer
Location:
3p21.1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (52833115..52897581, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (52867131..52931597, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene inter-alpha-trypsin inhibitor heavy chain 3 Neighboring gene ITIH4 antisense RNA 1 Neighboring gene inter-alpha-trypsin inhibitor heavy chain family member 4 Neighboring gene musculoskeletal, embryonic nuclear protein 1 Neighboring gene STIM activating enhancer Neighboring gene microRNA 8064 Neighboring gene Scm like with four mbt domains 1 Neighboring gene SERPINE1 mRNA binding protein 1 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
NHGRI GWA Catalog
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
NHGRI GWA Catalog

General gene information

Markers

Homology

Clone Names

  • DKFZp667E1121

General protein information

Preferred Names
TMEM110-MUSTN1 fusion protein
Names
TMEM110-MUSTN1 read-through transcript

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198974.2NP_001185903.2  TMEM110-MUSTN1 fusion protein

    Status: VALIDATED

    Source sequence(s)
    AC099667
    Consensus CDS
    CCDS56264.1
    UniProtKB/TrEMBL
    A8MSY1
    Related
    ENSP00000422941.1, OTTHUMP00000218922, ENST00000504329.1, OTTHUMT00000362140
    Conserved Domains (2) summary
    pfam12400
    Location:100219
    DUF3661; Vaculolar membrane protein
    pfam15682
    Location:298372
    Mustang; Musculoskeletal, temporally activated-embryonic nuclear protein 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    52833115..52897581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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