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KIF21A kinesin family member 21A [ Sus scrofa (pig) ]

Gene ID: 100520674, updated on 1-Mar-2025

Summary

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Official Symbol
KIF21Aprovided by VGNC
Official Full Name
kinesin family member 21Aprovided by VGNC
Primary source
VGNC:VGNC:89464
See related
Ensembl:ENSSSCG00000000779 RGD:14214124
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in kidney (RPKM 6.3), mixtures (RPKM 4.6) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See KIF21A in Genome Data Viewer
Location:
chromosome: 5
Exon count:
38
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (70888999..71029832, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (73379320..73586144, complement)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene ribulose-phosphate 3-epimerase-like Neighboring gene copine 8 Neighboring gene ATP binding cassette subfamily D member 2 Neighboring gene regulator of DNA class I crossover intermediates 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. A 63-bp insertion in exon 2 of the porcine KIF21A gene is associated with arthrogryposis multiplex congenita. Fang ZH, et al. Anim Genet, 2020 Oct. PMID 32686171
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A 63-bp insertion in exon 2 of the porcine KIF21A gene is associated with arthrogryposis multiplex congenita.
    Title: A 63-bp insertion in exon 2 of the porcine KIF21A gene is associated with arthrogryposis multiplex congenita.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic spindle organization IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kinesin-like protein KIF21A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    70888999..71029832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013997931.2 → XP_013853385.2  kinesin-like protein KIF21A isoform X7

    UniProtKB/TrEMBL
    A0A8D1CMR1
    Conserved Domains (4) summary
    cd00200
    Location:1319 → 1632
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1370 → 1429
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_021092529.1 → XP_020948188.1  kinesin-like protein KIF21A isoform X13

    UniProtKB/TrEMBL
    A0A8D1YMH7, A0A8W4FKT7
    Related
    ENSSSCP00000079522.1, ENSSSCT00000093416.1
    Conserved Domains (4) summary
    cd00200
    Location:1283 → 1596
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1334 → 1393
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  3. XM_013997935.2 → XP_013853389.2  kinesin-like protein KIF21A isoform X9

    UniProtKB/TrEMBL
    A0A4X1U8P2, A0A8D0VPP4
    Related
    ENSSSCP00000065577.2, ENSSSCT00000083953.2
    Conserved Domains (4) summary
    cd00200
    Location:1308 → 1621
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1359 → 1418
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_013997930.2 → XP_013853384.2  kinesin-like protein KIF21A isoform X5

    UniProtKB/TrEMBL
    A0A8D1CMR1
    Conserved Domains (4) summary
    cd00200
    Location:1325 → 1638
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1376 → 1435
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  5. XM_021092530.1 → XP_020948189.1  kinesin-like protein KIF21A isoform X15

    UniProtKB/TrEMBL
    A0A4X1U6Q9
    Related
    ENSSSCP00000065615.2, ENSSSCT00000071566.2
    Conserved Domains (4) summary
    cd00200
    Location:1271 → 1584
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1322 → 1381
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  6. XM_021092527.1 → XP_020948186.1  kinesin-like protein KIF21A isoform X8

    UniProtKB/TrEMBL
    A0A8D0S7G8, A0A8D1KV87
    Conserved Domains (4) summary
    cd00200
    Location:1314 → 1627
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1365 → 1424
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  7. XM_013997928.2 → XP_013853382.2  kinesin-like protein KIF21A isoform X3

    UniProtKB/TrEMBL
    A0A4X1U4I2, A0A8D1C089
    Conserved Domains (4) summary
    cd00200
    Location:1332 → 1645
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1383 → 1442
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  8. XM_013997934.2 → XP_013853388.2  kinesin-like protein KIF21A isoform X14

    UniProtKB/TrEMBL
    A0A4X1U6Q9
    Conserved Domains (4) summary
    cd00200
    Location:1278 → 1591
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1329 → 1388
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  9. XM_021092528.1 → XP_020948187.1  kinesin-like protein KIF21A isoform X12

    UniProtKB/TrEMBL
    A0A4X1U6Q9
    Conserved Domains (4) summary
    cd00200
    Location:1295 → 1608
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1346 → 1405
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  10. XM_013997933.2 → XP_013853387.2  kinesin-like protein KIF21A isoform X11

    UniProtKB/TrEMBL
    A0A4X1U6Q9
    Conserved Domains (4) summary
    cd00200
    Location:1296 → 1609
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1347 → 1406
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  11. XM_021092526.1 → XP_020948185.1  kinesin-like protein KIF21A isoform X6

    UniProtKB/TrEMBL
    A0A8D1KV87
    Conserved Domains (4) summary
    cd00200
    Location:1321 → 1634
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1372 → 1431
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  12. XM_013997927.2 → XP_013853381.2  kinesin-like protein KIF21A isoform X1

    UniProtKB/TrEMBL
    A0A4X1U4I2, A0A8D1C089
    Related
    ENSSSCP00000073785.2, ENSSSCT00000086842.2
    Conserved Domains (4) summary
    cd00200
    Location:1339 → 1652
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1390 → 1449
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain

  13. XM_013997932.2 → XP_013853386.2  kinesin-like protein KIF21A isoform X10

    UniProtKB/TrEMBL
    A0A287AI15, A0A4X1U8P2, A0A8D0VPP4, A0A8D1YE96
    Related
    ENSSSCP00000043677.1, ENSSSCT00000053315.1
    Conserved Domains (4) summary
    cd00200
    Location:1301 → 1614
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1352 → 1411
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  14. XM_013997929.2 → XP_013853383.2  kinesin-like protein KIF21A isoform X4

    UniProtKB/TrEMBL
    A0A8D1CMR1, F1SHQ3
    Related
    ENSSSCP00000000826.5, ENSSSCT00000000843.5
    Conserved Domains (4) summary
    cd00200
    Location:1326 → 1639
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1377 → 1436
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:364 → 1025
    SMC_N; RecF/RecN/SMC N terminal domain

  15. XM_003126606.6 → XP_003126654.5  kinesin-like protein KIF21A isoform X2

    UniProtKB/TrEMBL
    A0A4X1U4I2, A0A8D1C089, A0A8D1YJB4
    Conserved Domains (4) summary
    cd00200
    Location:1338 → 1651
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd01372
    Location:8 → 372
    KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
    sd00039
    Location:1389 → 1448
    7WD40; WD40 repeat [structural motif]
    cl25732
    Location:640 → 1038
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
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