EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit [Sus scrofa (pig)] - Gene

Summary

Official Symbol: EZH1provided by VGNC
Official Full Name: enhancer of zeste 1 polycomb repressive complex 2 subunitprovided by VGNC
Primary source: VGNC:VGNC:87854
See related: Ensembl:ENSSSCG00000017382
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Ubiquitous expression in subcutaneous adipose (RPKM 23.3), lung (RPKM 21.5) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	12	NC_010454.4 (20107744..20139764)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	12	NC_010454.3 (20304800..20338128, complement)

Chromosome 12 - NC_010454.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BARC0021 (e-PCR)
- UniSTS:255307

MARC_15753-15754:1017935735:1 (e-PCR)
- UniSTS:267893

MARC_15753-15754:1032191159:1 (e-PCR)
- UniSTS:267893

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables histone H3K27 methyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: histone-lysine N-methyltransferase EZH1

Names: enhancer of zeste homolog 1

NP_001230135.1

EC 2.1.1.354

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243206.1 → NP_001230135.1 histone-lysine N-methyltransferase EZH1

See identical proteins and their annotated locations for NP_001230135.1

Status: VALIDATED

Source sequence(s)

CU928483

UniProtKB/TrEMBL

A0A8D0IP85, A0A8D0Y904

Related

ENSSSCP00000018416.4, ENSSSCT00000018921.5

Conserved Domains (4) summary

smart00717
Location:433 → 474

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

smart00317
Location:617 → 738

SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain

cd00167
Location:433 → 474

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

pfam11616
Location:39 → 67

EZH2_WD-Binding; WD repeat binding protein EZH2