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TUNAR TCL1 upstream neural differentiation-associated RNA [ Homo sapiens (human) ]

Gene ID: 100507043, updated on 13-May-2022

Summary

Official Symbol
TUNARprovided by HGNC
Official Full Name
TCL1 upstream neural differentiation-associated RNAprovided by HGNC
Primary source
HGNC:HGNC:44088
See related
Ensembl:ENSG00000250366 MIM:615719; AllianceGenome:HGNC:44088
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BNLN; TUNA; HI-LNC78; LINC00617
Summary
This gene produces a spliced long non-coding RNA that may play a role in maintaining pluripotency and the neural differentiation of embryonic stem cells. Expression of this lncRNA in the caudate nucleus of brains from Huntington's Disease patients has been found to decrease as the disease progresses. It has also been suggested that this transcript may play a role in the progression of breast cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2015]
Expression
Biased expression in endometrium (RPKM 5.7), brain (RPKM 3.3) and 3 other tissues See more
Orthologs
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Genomic context

See TUNAR in Genome Data Viewer
Location:
14q32.2
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (95876392..95925571)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (90107903..90157077)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (96342729..96391908)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984703 Neighboring gene uncharacterized LOC105370644 Neighboring gene chromosome 14 open reading frame 132 Neighboring gene uncharacterized LOC124903374

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Other Names

  • Human Islet Long Non Coding RNA 78
  • Tcl1 upstream neuron-associated lincRNA
  • beta cell- and neural cell-regulin
  • long intergenic non-protein coding RNA 617

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038861.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks one internal exon, compared to variant 1.
    Source sequence(s)
    AK023027, BC016484, DA412350
    Related
    ENST00000503525.2
  2. NR_132398.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AK023027, BC016484, DA408223, DA412350
  3. NR_132399.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks two exons and includes an alternate 5' terminal exon, compared to variant 1.
    Source sequence(s)
    AK023027, BC016484
    Related
    ENST00000504119.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    95876392..95925571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    90107903..90157077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)