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SLFN12L schlafen family member 12 like [ Homo sapiens (human) ]

Gene ID: 100506736, updated on 4-Nov-2022

Summary

Official Symbol
SLFN12Lprovided by HGNC
Official Full Name
schlafen family member 12 likeprovided by HGNC
Primary source
HGNC:HGNC:33920
See related
Ensembl:ENSG00000205045 MIM:614956; AllianceGenome:HGNC:33920
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in spleen (RPKM 1.6), lymph node (RPKM 1.2) and 20 other tissues See more
Orthologs
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Genomic context

See SLFN12L in Genome Data Viewer
Location:
17q12
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (35464254..35537678, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (36412245..36485638, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (33791273..33864697, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene schlafen family member 13 Neighboring gene adenylosuccinate synthase 2 pseudogene Neighboring gene E2F transcription factor 3 pseudogene 1 Neighboring gene TATA-box binding protein associated factor 5 like pseudogene 1 Neighboring gene mitochondrial import receptor subunit TOM20 homolog Neighboring gene uncharacterized LOC107985033 Neighboring gene schlafen family member 14 Neighboring gene ribosomal protein L39 pseudogene 32

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23922

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
schlafen family member 12-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195790.3NP_001182719.2  schlafen family member 12-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC015911
    Consensus CDS
    CCDS56026.2
    UniProtKB/TrEMBL
    A0A499FJ85
    Related
    ENSP00000437635.2, ENST00000260908.13
    Conserved Domains (1) summary
    PHA02782
    Location:17341
    PHA02782; hypothetical protein; Provisional
  2. NM_001363830.2NP_001350759.2  schlafen family member 12-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC015911
    Consensus CDS
    CCDS86591.2
    UniProtKB/TrEMBL
    A0A8I5QCZ1
    Related
    ENSP00000487397.4, ENST00000628453.4
    Conserved Domains (1) summary
    PHA02782
    Location:59383
    PHA02782; hypothetical protein; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    35464254..35537678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    36412245..36485638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001145027.1: Suppressed sequence

    Description
    NM_001145027.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.