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SPMAP2L sperm microtubule associated protein 2 like [ Homo sapiens (human) ]

Gene ID: 100506564, updated on 10-Dec-2024

Summary

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Official Symbol
SPMAP2Lprovided by HGNC
Official Full Name
sperm microtubule associated protein 2 likeprovided by HGNC
Primary source
HGNC:HGNC:43771
See related
Ensembl:ENSG00000249693 AllianceGenome:HGNC:43771
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
THEGL
Expression
Biased expression in testis (RPKM 1.0) and skin (RPKM 0.1) See more
Orthologs
mouse all
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Genomic context

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See SPMAP2L in Genome Data Viewer
Location:
4q12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (56530606..56626214)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (60018614..60114234)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (57396772..57469673)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21580 Neighboring gene signal recognition particle 72 Neighboring gene uncharacterized LOC105377665 Neighboring gene ARF like GTPase 9 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:57397246-57397779 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15451 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:57424181-57424393 Neighboring gene NANOG hESC enhancer GRCh37_chr4:57472386-57472887 Neighboring gene glycine decarboxylase pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15452 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:57501823-57502323 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:57506917-57508116 Neighboring gene uncharacterized LOC124900708 Neighboring gene hESC enhancers GRCh37_chr4:57528805-57529620 and GRCh37_chr4:57529621-57530435 Neighboring gene HOP homeobox Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15453 Neighboring gene uncharacterized LOC105377666 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:57559757-57560564

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly. Ertych N, et al. Proc Natl Acad Sci U S A, 2016 Feb 16. PMID 26831064, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
sperm microtubule associated protein 2-like
Names
testicular haploid expressed gene protein-like
theg spermatid protein like
theg spermatid-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256475.2 → NP_001243404.1  sperm microtubule associated protein 2-like

    See identical proteins and their annotated locations for NP_001243404.1

    Status: VALIDATED

    Source sequence(s)
    AC108215, DB450279, DW009623, DY655427, DY655539
    Consensus CDS
    CCDS58899.1
    UniProtKB/Swiss-Prot
    P0DJG4
    Related
    ENSP00000456850.1, ENST00000512175.3
    Conserved Domains (1) summary
    pfam14912
    Location:404 → 462
    THEG; Testicular haploid expressed repeat

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    56530606..56626214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011534357.2 → XP_011532659.1  sperm microtubule associated protein 2-like isoform X1

    Conserved Domains (1) summary
    pfam14912
    Location:210 → 277
    THEG; Testicular haploid expressed repeat

  2. XM_011534361.3 → XP_011532663.1  sperm microtubule associated protein 2-like isoform X2

    Conserved Domains (1) summary
    pfam14912
    Location:210 → 277
    THEG; Testicular haploid expressed repeat

  3. XM_011534363.3 → XP_011532665.1  sperm microtubule associated protein 2-like isoform X3

    Conserved Domains (1) summary
    pfam14912
    Location:210 → 277
    THEG; Testicular haploid expressed repeat

  4. XM_011534364.2 → XP_011532666.1  sperm microtubule associated protein 2-like isoform X4

    Conserved Domains (1) summary
    pfam14912
    Location:210 → 277
    THEG; Testicular haploid expressed repeat

  5. XM_011534365.3 → XP_011532667.1  sperm microtubule associated protein 2-like isoform X5

    Conserved Domains (1) summary
    pfam14912
    Location:210 → 277
    THEG; Testicular haploid expressed repeat

RNA

  1. XR_941041.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    60018614..60114234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054348689.1 → XP_054204664.1  sperm microtubule associated protein 2-like isoform X1

  2. XM_054348690.1 → XP_054204665.1  sperm microtubule associated protein 2-like isoform X2

  3. XM_054348691.1 → XP_054204666.1  sperm microtubule associated protein 2-like isoform X3

  4. XM_054348692.1 → XP_054204667.1  sperm microtubule associated protein 2-like isoform X4

  5. XM_054348693.1 → XP_054204668.1  sperm microtubule associated protein 2-like isoform X5

RNA

  1. XR_008486887.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DJG4.1 GenPept UniProtKB/Swiss-Prot:P0DJG4

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