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SPATA1 spermatogenesis associated 1 [ Homo sapiens (human) ]

Gene ID: 100505741, updated on 6-Nov-2022

Summary

Official Symbol
SPATA1provided by HGNC
Official Full Name
spermatogenesis associated 1provided by HGNC
Primary source
HGNC:HGNC:14682
See related
Ensembl:ENSG00000122432 AllianceGenome:HGNC:14682
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SP-2; SPAP1
Expression
Broad expression in colon (RPKM 6.0), testis (RPKM 4.7) and 22 other tissues See more
Orthologs
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Genomic context

See SPATA1 in Genome Data Viewer
Location:
1p22.3
Exon count:
17
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (84506386..84567379)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (84346767..84407753)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (84972069..85033062)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 5400 Neighboring gene deoxyribonuclease 2 beta Neighboring gene ribosome production factor 1 homolog Neighboring gene G protein subunit gamma 5 Neighboring gene chitobiase Neighboring gene uncharacterized LOC105378819 Neighboring gene long intergenic non-protein coding RNA 1461

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC157666

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in acrosomal vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
spermatogenesis-associated protein 1
Names
sperm-specific protein SP-2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310156.2NP_001297085.2  spermatogenesis-associated protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL359762
    Conserved Domains (1) summary
    pfam15743
    Location:279428
    SPATA1_C; Spermatogenesis-associated C-terminus
  2. NM_001397487.1NP_001384416.1  spermatogenesis-associated protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL359762
    Consensus CDS
    CCDS90993.1
    Related
    ENSP00000514414.1, ENST00000699524.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    84506386..84567379
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542514.3XP_011540816.1  spermatogenesis-associated protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011540816.1

    Conserved Domains (1) summary
    pfam15743
    Location:297408
    SPATA1_C; Spermatogenesis-associated C-terminus
  2. XM_024446289.2XP_024302057.1  spermatogenesis-associated protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9HAR4
    Related
    ENST00000490879.9
    Conserved Domains (1) summary
    pfam15743
    Location:301450
    SPATA1_C; Spermatogenesis-associated C-terminus
  3. XM_011542517.2XP_011540819.1  spermatogenesis-associated protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011540819.1

    UniProtKB/Swiss-Prot
    Q5VX52
  4. XM_011542516.2XP_011540818.1  spermatogenesis-associated protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011540818.1

    UniProtKB/Swiss-Prot
    Q5VX52
  5. XM_047416131.1XP_047272087.1  spermatogenesis-associated protein 1 isoform X6

  6. XM_047416077.1XP_047272033.1  spermatogenesis-associated protein 1 isoform X4

  7. XM_047416194.1XP_047272150.1  spermatogenesis-associated protein 1 isoform X7

  8. XM_011542519.3XP_011540821.1  spermatogenesis-associated protein 1 isoform X5

    See identical proteins and their annotated locations for XP_011540821.1

  9. XM_011542515.3XP_011540817.1  spermatogenesis-associated protein 1 isoform X3

    See identical proteins and their annotated locations for XP_011540817.1

  10. XM_011542522.3XP_011540824.1  spermatogenesis-associated protein 1 isoform X8

    See identical proteins and their annotated locations for XP_011540824.1

    Related
    ENSP00000514413.1, ENST00000697276.1

RNA

  1. XR_007057962.1 RNA Sequence

  2. XR_007057965.1 RNA Sequence

  3. XR_007057967.1 RNA Sequence

  4. XR_947545.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    84346767..84407753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081472.1: Suppressed sequence

    Description
    NM_001081472.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
  2. NM_022354.1: Suppressed sequence

    Description
    NM_022354.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.