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Smim27 small integral membrane protein 27 [ Mus musculus (house mouse) ]

Gene ID: 100504309, updated on 8-Mar-2024


Official Symbol
Smim27provided by MGI
Official Full Name
small integral membrane protein 27provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000028407 AllianceGenome:MGI:1913684
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Toporsos; 2010003O02Rik
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SMIM27 (small integral membrane protein 27). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in adrenal adult (RPKM 44.5), ovary adult (RPKM 42.6) and 28 other tissues See more
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Genomic context

4 20.24 cM; 4 A5
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (40269579..40270228)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (40269579..40270228)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene aconitase 1 Neighboring gene STARR-seq mESC enhancer starr_09982 Neighboring gene RNA sensor RIG-I Neighboring gene STARR-seq mESC enhancer starr_09983 Neighboring gene STARR-positive B cell enhancer ABC_E6161 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:40216827-40216936 Neighboring gene topoisomerase I binding, arginine/serine-rich Neighboring gene STARR-seq mESC enhancer starr_09984 Neighboring gene NADH:ubiquinone oxidoreductase subunit B6 Neighboring gene RIKEN cDNA 4930509K18 gene Neighboring gene STARR-seq mESC enhancer starr_09985

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
small integral membrane protein 27
TOPORS antisense RNA 1
Topors opposite strand transcript
topoisomerase I binding, arginine/serine-rich, opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001349093.1NP_001336022.1  small integral membrane protein 27

    Status: VALIDATED

    Source sequence(s)
    AA190030, AL831793
    Consensus CDS
    ENSMUSP00000146567.2, ENSMUST00000129758.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000070.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_045265.1: Suppressed sequence

    NR_045265.1: This RefSeq was removed because it is now thought that this gene does encode a protein.