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Fam181a family with sequence similarity 181, member A [ Mus musculus (house mouse) ]

Gene ID: 100504156, updated on 8-Mar-2024

Summary

Official Symbol
Fam181aprovided by MGI
Official Full Name
family with sequence similarity 181, member Aprovided by MGI
Primary source
MGI:MGI:3647570
See related
Ensembl:ENSMUSG00000096753 AllianceGenome:MGI:3647570
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG544888
Summary
Is expressed in several structures, including adrenal gland; brain; genitourinary system; liver; and neural ectoderm. Orthologous to human FAM181A (family with sequence similarity 181 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 49.5), CNS E11.5 (RPKM 9.2) and 2 other tissues See more
Orthologs
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Genomic context

See Fam181a in Genome Data Viewer
Location:
12 E; 12 52.9 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (103277272..103283326)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (103310966..103317067)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene unc-79 homolog Neighboring gene STARR-seq mESC enhancer starr_33121 Neighboring gene proline rich membrane anchor 1 Neighboring gene STARR-positive B cell enhancer ABC_E7173 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:104569739-104569961 Neighboring gene STARR-positive B cell enhancer ABC_E4038 Neighboring gene predicted gene 29508 Neighboring gene STARR-positive B cell enhancer ABC_E1863 Neighboring gene predicted gene 15523 Neighboring gene ankyrin repeat and SOCS box-containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E7174 Neighboring gene OTU domain, ubiquitin aldehyde binding 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195726.2NP_001182655.1  protein FAM181A

    See identical proteins and their annotated locations for NP_001182655.1

    Status: VALIDATED

    Source sequence(s)
    AC160131
    Consensus CDS
    CCDS56858.1
    UniProtKB/TrEMBL
    J3QNB7
    Related
    ENSMUSP00000136681.2, ENSMUST00000179363.2
    Conserved Domains (1) summary
    pfam15238
    Location:3280
    FAM181
  2. NM_001413260.1NP_001400189.1  protein FAM181A

    Status: VALIDATED

    Source sequence(s)
    AC160131
    UniProtKB/TrEMBL
    J3QNB7
  3. NM_001413261.1NP_001400190.1  protein FAM181A

    Status: VALIDATED

    Source sequence(s)
    AC160131
    UniProtKB/TrEMBL
    J3QNB7
  4. NM_001413262.1NP_001400191.1  protein FAM181A

    Status: VALIDATED

    Source sequence(s)
    AC160131
    UniProtKB/TrEMBL
    J3QNB7
    Related
    ENSMUSP00000140842.2, ENSMUST00000191218.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    103277272..103283326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515322.4XP_006515385.1  protein FAM181A isoform X1

    See identical proteins and their annotated locations for XP_006515385.1

    UniProtKB/TrEMBL
    J3QNB7
    Conserved Domains (1) summary
    pfam15238
    Location:3280
    FAM181
  2. XM_006515320.2XP_006515383.1  protein FAM181A isoform X1

    See identical proteins and their annotated locations for XP_006515383.1

    UniProtKB/TrEMBL
    J3QNB7
    Conserved Domains (1) summary
    pfam15238
    Location:3280
    FAM181