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Zfp683 zinc finger protein 683 [ Mus musculus (house mouse) ]

Gene ID: 100503878, updated on 11-Nov-2024

Summary

Official Symbol
Zfp683provided by MGI
Official Full Name
zinc finger protein 683provided by MGI
Primary source
MGI:MGI:3650254
See related
AllianceGenome:MGI:3650254
Gene type
pseudo
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hobit; Gm13060
Summary
Enables promoter-specific chromatin binding activity. Involved in regulation of gene expression and regulation of lymphocyte differentiation. Acts upstream of or within NK T cell differentiation and natural killer cell differentiation. Predicted to be located in nucleus. Orthologous to human ZNF683 (zinc finger protein 683). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Zfp683 in Genome Data Viewer
Location:
4 D2.3; 4 66.5 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133778506..133786252)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134051195..134058941)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene dehydrodolichyl diphosphate synthase Neighboring gene STARR-positive B cell enhancer ABC_E9085 Neighboring gene STARR-seq mESC enhancer starr_11665 Neighboring gene lin-28 homolog A Neighboring gene crystallin beta-gamma domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E1658 Neighboring gene STARR-positive B cell enhancer ABC_E9600 Neighboring gene CD52 antigen

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 
  • Gene trapped (1) 
  • Targeted (3)  1 citation

General gene information

Other Names

  • novel zinc finger protein

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables promoter-specific chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within NK T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in T cell receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to ionomycin ISO
Inferred from Sequence Orthology
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within natural killer cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of type II interferon production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of NK T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of extrathymic T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of natural killer cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of natural killer cell differentiation involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_031849.1 

    Range
    101..7847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    133778506..133786252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)