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Gng14 G protein subunit gamma 14 [ Mus musculus (house mouse) ]

Gene ID: 100503710, updated on 16-Mar-2024

Summary

Official Symbol
Gng14provided by MGI
Official Full Name
G protein subunit gamma 14provided by MGI
Primary source
MGI:MGI:3645690
See related
Ensembl:ENSMUSG00000095845 AllianceGenome:MGI:3645690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5741; EG436049
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Orthologous to human GNG14 (G protein subunit gamma 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 2.3), CNS E18 (RPKM 2.2) and 28 other tissues See more
Orthologs
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Genomic context

Location:
8; 8 C3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (85794141..85794647, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (85067568..85067982, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene transportin 2 (importin 3, karyopherin beta 2b) Neighboring gene RIKEN cDNA A230103J11 gene Neighboring gene STARR-seq mESC enhancer starr_22150 Neighboring gene F-box and WD-40 domain protein 9 Neighboring gene microRNA 7070 Neighboring gene deoxyhypusine synthase Neighboring gene WD repeat domain containing 83 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:87604516-87604669 Neighboring gene WD repeat domain 83 opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

General gene information

Clone Names

  • MGC182247, MGC182257

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195531.2NP_001182460.1  putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14

    See identical proteins and their annotated locations for NP_001182460.1

    Status: VALIDATED

    Source sequence(s)
    AC163703
    Consensus CDS
    CCDS57629.1
    UniProtKB/TrEMBL
    B2RVA4
    Related
    ENSMUSP00000136655.2, ENSMUST00000177563.2
    Conserved Domains (1) summary
    smart00224
    Location:1172
    GGL; G protein gamma subunit-like motifs

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    85794141..85794647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)