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Tmem95 transmembrane protein 95 [ Mus musculus (house mouse) ]

Gene ID: 100503361, updated on 18-Apr-2024

Summary

Official Symbol
Tmem95provided by MGI
Official Full Name
transmembrane protein 95provided by MGI
Primary source
MGI:MGI:3779488
See related
Ensembl:ENSMUSG00000094845 AllianceGenome:MGI:3779488
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
432576
Summary
Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Located in acrosomal membrane. Orthologous to human TMEM95 (transmembrane protein 95). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 12.5) and stomach adult (RPKM 0.4) See more
Orthologs
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Genomic context

Location:
11 B3; 11 42.91 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69766880..69768997, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69876054..69878171, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene phospholipid scramblase 3 Neighboring gene tyrosine kinase, non-receptor, 1 Neighboring gene predicted gene, 32708 Neighboring gene STARR-seq mESC enhancer starr_29868 Neighboring gene potassium channel tetramerisation domain containing 11 Neighboring gene microRNA 6924 Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in acrosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in acrosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in sperm plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sperm-egg fusion protein TMEM95

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195710.2NP_001182639.1  sperm-egg fusion protein TMEM95 precursor

    See identical proteins and their annotated locations for NP_001182639.1

    Status: VALIDATED

    Source sequence(s)
    AL845465
    Consensus CDS
    CCDS56783.1
    UniProtKB/Swiss-Prot
    P0DJF3
    Related
    ENSMUSP00000137492.2, ENSMUST00000178597.3
    Conserved Domains (1) summary
    pfam15203
    Location:17168
    TMEM95; TMEM95 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    69766880..69768997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156170.1XP_036012063.1  sperm-egg fusion protein TMEM95 isoform X2

    Conserved Domains (1) summary
    pfam15203
    Location:17111
    TMEM95; TMEM95 family
  2. XM_006531882.4XP_006531945.1  sperm-egg fusion protein TMEM95 isoform X1

    See identical proteins and their annotated locations for XP_006531945.1

    Conserved Domains (1) summary
    pfam15203
    Location:17142
    TMEM95; TMEM95 family