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Pou2af3 POU class 2 homeobox associating factor 3 [ Mus musculus (house mouse) ]

Gene ID: 100502940, updated on 9-May-2024

Summary

Official Symbol
Pou2af3provided by MGI
Official Full Name
POU class 2 homeobox associating factor 3provided by MGI
Primary source
MGI:MGI:2685530
See related
Ensembl:ENSMUSG00000079559 AllianceGenome:MGI:2685530
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm684; Colca2; OCA-T2
Summary
Predicted to be active in cytoplasm. Orthologous to human COLCA2 (colorectal cancer associated 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 3.3), genital fat pad adult (RPKM 3.2) and 21 other tissues See more
Orthologs
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Genomic context

See Pou2af3 in Genome Data Viewer
Location:
9 A5.3; 9 28.02 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (51181558..51189865, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (51270258..51278565, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10544 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:50973591-50973879 Neighboring gene predicted gene, 32742 Neighboring gene STARR-seq mESC enhancer starr_24126 Neighboring gene STARR-positive B cell enhancer ABC_E6731 Neighboring gene STARR-positive B cell enhancer ABC_E10545 Neighboring gene STARR-positive B cell enhancer ABC_E6732 Neighboring gene POU domain, class 2, associating factor 1 Neighboring gene STARR-seq mESC enhancer starr_24127 Neighboring gene predicted gene, 32819 Neighboring gene POU domain, class 2, associating factor 2 Neighboring gene predicted gene, 39338 Neighboring gene STARR-seq mESC enhancer starr_24128 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:51209953-51210278 Neighboring gene STARR-seq mESC enhancer starr_24129 Neighboring gene STARR-seq mESC enhancer starr_24130 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables POU domain binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
POU Class 2 homeobox-associating factor 3
Names
COLCA2 homolog
colorectal cancer-associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195681.2NP_001182610.1  POU Class 2 homeobox-associating factor 3

    See identical proteins and their annotated locations for NP_001182610.1

    Status: VALIDATED

    Source sequence(s)
    AC160052
    Consensus CDS
    CCDS57676.1
    UniProtKB/Swiss-Prot
    A0A6I8MWX2, F8VPY8
    Related
    ENSMUSP00000110070.4, ENSMUST00000114427.4
  2. NM_001409957.1NP_001396886.1  POU Class 2 homeobox-associating factor 3

    Status: VALIDATED

    Source sequence(s)
    AC160052
    Related
    ENSMUSP00000150539.2, ENSMUST00000215038.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    51181558..51189865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509896.5XP_006509959.1  POU Class 2 homeobox-associating factor 3 isoform X2

    See identical proteins and their annotated locations for XP_006509959.1

    UniProtKB/Swiss-Prot
    A0A6I8MWX2, F8VPY8
    Related
    ENSMUSP00000159303.2, ENSMUST00000239415.2
  2. XM_011242373.3XP_011240675.1  POU Class 2 homeobox-associating factor 3 isoform X1

    UniProtKB/Swiss-Prot
    A0A6I8MWX2, F8VPY8
  3. XM_011242374.3XP_011240676.1  POU Class 2 homeobox-associating factor 3 isoform X3

    See identical proteins and their annotated locations for XP_011240676.1

    UniProtKB/Swiss-Prot
    A0A6I8MWX2, F8VPY8
  4. XM_011242375.3XP_011240677.1  POU Class 2 homeobox-associating factor 3 isoform X3

    See identical proteins and their annotated locations for XP_011240677.1

    UniProtKB/Swiss-Prot
    A0A6I8MWX2, F8VPY8