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MIR378-2 microRNA mir-378-2 [ Bos taurus (domestic cattle) ]

Gene ID: 100498808, updated on 4-Oct-2024

Summary

Gene symbol
MIR378-2
Gene description
microRNA mir-378-2
See related
Ensembl:ENSBTAG00000053622 miRBase:MI0013052
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
mir-378-2; bta-mir-378-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR378-2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (10883955..10884030)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene calcitonin receptor Neighboring gene microRNA mir-653 Neighboring gene microRNA mir-489 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene tissue factor pathway inhibitor 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036345.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000004
    Related
    ENSBTAT00000079613.1

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    10883955..10884030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)