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sirt2 sirtuin 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100489469, updated on 8-Mar-2024

Summary

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Official Symbol
sirt2provided by Xenbase
Official Full Name
sirtuin 2provided by Xenbase
Primary source
Xenbase:XB-GENE-987375
See related
Ensembl:ENSXETG00000002409
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
sir2; xsirt2; sirtuin
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (55087418..55102956)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (68331628..68347210)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 183A Neighboring gene ras and Rab interactor 3 Neighboring gene G protein-coupled receptor 161 Neighboring gene dermatopontin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
  
enables NAD-dependent histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    55087418..55102956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004910718.4 → XP_004910775.1  NAD-dependent protein deacetylase sirtuin-2 isoform X2

    UniProtKB/TrEMBL
    A0A6I8QQ12, A0A8J0QZE9
    Conserved Domains (1) summary
    cd01408
    Location:39 → 292
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  2. XM_002935781.5 → XP_002935827.4  NAD-dependent protein deacetylase sirtuin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8J0QND7, F6U8M9
    Related
    ENSXETP00000005130.3, ENSXETT00000005130.4
    Conserved Domains (1) summary
    cd01408
    Location:89 → 342
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...
Nucleotide Protein Strain
Heading Accession and Version

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