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gfra4 GDNF family receptor alpha 4 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100487002, updated on 4-Jan-2025

Summary

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Official Symbol
gfra4provided by Xenbase
Official Full Name
GDNF family receptor alpha 4provided by Xenbase
Primary source
Xenbase:XB-GENE-854948
See related
Ensembl:ENSXETG00000004362 AllianceGenome:Xenbase:XB-GENE-854948
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable glial cell-derived neurotrophic factor receptor activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human GFRA4 (GDNF family receptor alpha 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See gfra4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (13413242..13636851)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (7239445..7451916)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 127 Neighboring gene uncharacterized LOC116408421 Neighboring gene attractin Neighboring gene dynein axonemal assembly factor 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables glial cell-derived neurotrophic factor receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GDNF family receptor alpha-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    13413242..13636851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002936367.4 → XP_002936413.1  GDNF family receptor alpha-4

    UniProtKB/TrEMBL
    A0A6I8PT46, A0A803JCG4
    Related
    ENSXETP00000057057.3, ENSXETT00000057057.4
    Conserved Domains (1) summary
    pfam02351
    Location:264 → 358
    GDNF; GDNF/GAS1 domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials