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hspa1b heat shock protein family A (Hsp70) member 1B [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100485441, updated on 6-Jul-2026
Official Symbol
hspa1bprovided by Xenbase
Official Full Name
heat shock protein family A (Hsp70) member 1Bprovided by Xenbase
Primary source
Xenbase:XB-GENE-5915622
See related
AllianceGenome:Xenbase:XB-GENE-5915622
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable ATP binding activity and ATP-dependent protein folding chaperone. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1L (heat shock protein family A (Hsp70) member 1 like); HSPA1A (heat shock protein family A (Hsp70) member 1A); and HSPA1B (heat shock protein family A (Hsp70) member 1B). [provided by Alliance of Genome Resources, Jul 2025]
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Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (23980248..23982587)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (14610353..14612774)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene 6-pyruvoyltetrahydropterin synthase Neighboring gene proteasome 26S subunit, non-ATPase 13 Neighboring gene sirtuin 3

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
heat shock 70 kDa protein
Names
heat shock 70kDa protein 1B

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    23980248..23982587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002937639.5XP_002937685.2  heat shock 70 kDa protein

    UniProtKB/TrEMBL
    A0A8J0QQQ6
    Conserved Domains (1) summary
    PTZ00009
    Location:2643
    PTZ00009; heat shock 70 kDa protein; Provisional