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PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100483828, updated on 8-Mar-2024

Summary

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Gene symbol
PIK3R1
Gene description
phosphoinositide-3-kinase regulatory subunit 1
Locus tag
PANDA_003961
See related
Ensembl:ENSAMEG00000003039
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
19
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 3 NC_048220.1 (46404565..46486846)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003217398.1 (1288067..1367311)

Chromosome 3 - NC_048220.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117801509 Neighboring gene 40S ribosomal protein S20-like Neighboring gene uncharacterized LOC117801510 Neighboring gene uncharacterized LOC117801393

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048220.1 Reference ASM200744v2 Primary Assembly

    Range
    46404565..46486846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034656312.1 → XP_034512203.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

    UniProtKB/TrEMBL
    D2H2T5, G1L8J9
    Related
    ENSAMEP00000003218.2, ENSAMET00000003349.2

  2. XM_034656311.1 → XP_034512202.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

    UniProtKB/TrEMBL
    D2H2T5, G1L8J9

  3. XM_002915883.4 → XP_002915929.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

    UniProtKB/TrEMBL
    D2H2T5, G1L8J9
    Conserved Domains (6) summary
    cd09930
    Location:618 → 721
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:326 → 436
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11910
    Location:5 → 79
    SH3_PI3K_p85alpha; Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12924
    Location:441 → 601
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
    cd04388
    Location:116 → 309
    RhoGAP_p85; RhoGAP_p85: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region ...
    pfam16454
    Location:440 → 599
    PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

  4. XM_034656313.1 → XP_034512204.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A7N5KRW3
    Related
    ENSAMEP00000043933.1, ENSAMET00000039952.1

  5. XM_019796031.2 → XP_019651590.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3

    UniProtKB/TrEMBL
    G1L8K7
    Related
    ENSAMEP00000003226.1, ENSAMET00000003357.2
Nucleotide Protein
Heading Accession and Version

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