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THBS2 thrombospondin 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100455895, updated on 26-Mar-2024

Summary

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Gene symbol
THBS2
Gene description
thrombospondin 2
Locus tag
CR201_G0044857
See related
Ensembl:ENSPPYG00000017264
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 5 NC_071990.2 (171206386..171245887, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 6 NC_071991.1 (170594726..170634200, complement)

Chromosome 5 - NC_071990.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129059806 Neighboring gene uncharacterized LOC103891045 Neighboring gene uncharacterized LOC112133779 Neighboring gene WD repeat domain 27 Neighboring gene chromosome 5 C6orf120 homolog Neighboring gene PHD finger protein 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombospondin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071990.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    171206386..171245887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024248277.3 → XP_024104045.1  thrombospondin-2

    UniProtKB/TrEMBL
    A0A2J8S9X7, H2PL78
    Related
    ENSPPYP00000019356.3
    Conserved Domains (10) summary
    smart00209
    Location:497 → 549
    TSP1; Thrombospondin type 1 repeats
    smart00210
    Location:20 → 215
    TSPN; Thrombospondin N-terminal -like domains
    sd00001
    Location:847 → 884
    TSP3; TSP3 repeat_long [structural motif]
    sd00002
    Location:789 → 823
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:693 → 728
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam00093
    Location:320 → 374
    VWC; von Willebrand factor type C domain
    pfam00090
    Location:385 → 430
    TSP_1; Thrombospondin type 1 domain
    pfam02412
    Location:847 → 884
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:974 → 1171
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:652 → 691
    EGF_3; EGF domain
Nucleotide Protein
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