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PIAS1 protein inhibitor of activated STAT 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100450652, updated on 9-Oct-2018

Summary

Gene symbol
PIAS1
Gene description
protein inhibitor of activated STAT 1
Locus tag
CR201_G0028654
See related
Ensembl:ENSPPYG00000006589
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs

Genomic context

See PIAS1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Susie_PABv2 (GCF_002880775.1) 15 NC_036918.1 (48302466..48435779)
102 previous assembly P_pygmaeus_2.0.2 (GCF_000001545.4) 15 NC_012606.1 (65215095..65347671)

Chromosome 15 - NC_036918.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103892545 Neighboring gene U6 spliceosomal RNA Neighboring gene calmodulin like 4 Neighboring gene CLN6, transmembrane ER protein Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Hepatitis C, organism-specific biosystem (from KEGG)
    Hepatitis C, organism-specific biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
  • Hepatitis C, conserved biosystem (from KEGG)
    Hepatitis C, conserved biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
  • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
    Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
    Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
    Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
  • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
    Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

General gene information

Markers

Homology

General protein information

Preferred Names
E3 SUMO-protein ligase PIAS1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Pongo abelii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Susie_PABv2 Primary Assembly

Genomic

  1. NC_036918.1 Reference Susie_PABv2 Primary Assembly

    Range
    48302466..48435779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002825590.4XP_002825636.1  E3 SUMO-protein ligase PIAS1 isoform X2

    See identical proteins and their annotated locations for XP_002825636.1

    Related
    ENSPPYP00000007471
    Conserved Domains (3) summary
    smart00513
    Location:1145
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    pfam14324
    Location:137271
    PINIT; PINIT domain
    cd16790
    Location:332379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
  2. XM_002825591.4XP_002825637.1  E3 SUMO-protein ligase PIAS1 isoform X1

    See identical proteins and their annotated locations for XP_002825637.1

    Conserved Domains (3) summary
    smart00513
    Location:1347
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    pfam14324
    Location:139273
    PINIT; PINIT domain
    cd16790
    Location:334381
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
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