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KMT2A lysine methyltransferase 2A [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100441102, updated on 27-Jul-2017
Gene symbol
KMT2A
Gene description
lysine methyltransferase 2A
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Also known as
MLL
Orthologs
Location:
chromosome: 11
Exon count:
37
Annotation release Status Assembly Chr Location
102 current P_pygmaeus_2.0.2 (GCF_000001545.4) 11 NC_012602.1 (115379565..115470626)

Chromosome 11 - NC_012602.1Genomic Context describing neighboring genes Neighboring gene ubiquitination factor E4A Neighboring gene uncharacterized LOC103891922 Neighboring gene ATP synthase, H+ transporting, mitochondrial Fo complex subunit G Neighboring gene uncharacterized LOC103891923 Neighboring gene tetratricopeptide repeat domain 36 Neighboring gene transmembrane protein 25

Genomic Sequence:
NC_012602.1 Chromosome 11 Reference P_pygmaeus_2.0.2 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Preferred Names
LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2A
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

RefSeqs of Annotated Genomes: Pongo abelii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P_pygmaeus_2.0.2 Primary Assembly

Genomic

  1. NC_012602.1 Reference P_pygmaeus_2.0.2 Primary Assembly

    Range
    115379565..115470626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009247138.1XP_009245413.1  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2A

    Conserved Domains (11) summary
    cd05493
    Location:16541784
    Bromo_ALL-1; Bromodomain, ALL-1 like proteins. ALL-1 is a vertebrate homologue of Drosophila trithorax and is often affected in chromosomal rearrangements that are linked to acute leukemias, such as acute lymphocytic leukemia (ALL). Bromodomains are found in many ...
    smart00542
    Location:36763759
    FYRC; FY-rich domain, C-terminal region
    smart00317
    Location:38383958
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:39603976
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:38323976
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    pfam02008
    Location:11541201
    zf-CXXC; CXXC zinc finger domain
    cd15588
    Location:14401486
    PHD1_KMT2A; PHD finger 1 found in histone-lysine N-methyltransferase 2A (KMT2A)
    cd15590
    Location:14881537
    PHD2_KMT2A; PHD finger 2 found in histone-lysine N-methyltransferase 2A (KMT2A)
    cd15592
    Location:15751631
    PHD3_KMT2A; PHD finger 3 found in histone-lysine N-methyltransferase 2A (KMT2A)
    cd15693
    Location:18781990
    ePHD_KMT2A; Extended PHD finger found in histone-lysine N-methyltransferase 2A (KMT2A)
    pfam05964
    Location:20322078
    FYRN; F/Y-rich N-terminus
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