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AIFM3 apoptosis inducing factor mitochondria associated 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 100430573, updated on 17-Aug-2024
Official Symbol
AIFM3provided by VGNC
Official Full Name
apoptosis inducing factor mitochondria associated 3provided by VGNC
Primary source
VGNC:VGNC:69709
See related
Ensembl:ENSMMUG00000020478
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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See AIFM3 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (31761669..31778093)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (62647779..62665053, complement)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 29 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene THAP domain containing 7

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on NAD(P)H IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
apoptosis-inducing factor 3
Names
apoptosis-inducing factor, mitochondrion-associated, 3

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    31761669..31778093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028827953.1 → XP_028683786.1  apoptosis-inducing factor 3 isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZCN9
    Related
    ENSMMUP00000063378.1, ENSMMUT00000104853.1
    Conserved Domains (3) summary
    pfam07992
    Location:183 → 481
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:500 → 550
    Reductase_C; Reductase C-terminal
    cl00938
    Location:108 → 152
    Rieske; Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. ...

  2. XM_028827946.1 → XP_028683779.1  apoptosis-inducing factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5REC8, G7N3B3
    Related
    ENSMMUP00000058671.2, ENSMMUT00000062110.2
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  3. XM_028827949.1 → XP_028683782.1  apoptosis-inducing factor 3 isoform X3

    UniProtKB/TrEMBL
    G7N3B3, H9FQE7
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  4. XM_028827948.1 → XP_028683781.1  apoptosis-inducing factor 3 isoform X2

    UniProtKB/TrEMBL
    G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:195 → 491
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:510 → 560
    Reductase_C; Reductase C-terminal

  5. XM_028827956.1 → XP_028683789.1  apoptosis-inducing factor 3 isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZCN9
    Conserved Domains (3) summary
    pfam07992
    Location:183 → 481
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:500 → 550
    Reductase_C; Reductase C-terminal
    cl00938
    Location:108 → 152
    Rieske; Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. ...

  6. XM_028827947.1 → XP_028683780.1  apoptosis-inducing factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5REC8, G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  7. XM_015149787.2 → XP_015005273.1  apoptosis-inducing factor 3 isoform X2

    UniProtKB/TrEMBL
    G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:195 → 491
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:510 → 560
    Reductase_C; Reductase C-terminal

  8. XM_028827955.1 → XP_028683788.1  apoptosis-inducing factor 3 isoform X7

    UniProtKB/TrEMBL
    G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 553
    Reductase_C; Reductase C-terminal

  9. XM_015149789.2 → XP_015005275.1  apoptosis-inducing factor 3 isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZCN9
    Conserved Domains (3) summary
    pfam07992
    Location:183 → 481
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:500 → 550
    Reductase_C; Reductase C-terminal
    cl00938
    Location:108 → 152
    Rieske; Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. ...

  10. XM_002798284.3 → XP_002798330.1  apoptosis-inducing factor 3 isoform X1

    See identical proteins and their annotated locations for XP_002798330.1

    UniProtKB/TrEMBL
    A0A1D5REC8, G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  11. XM_002798286.2 → XP_002798332.1  apoptosis-inducing factor 3 isoform X6

    See identical proteins and their annotated locations for XP_002798332.1

    UniProtKB/TrEMBL
    F6VJW0
    Conserved Domains (5) summary
    pfam00070
    Location:322 → 402
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:183 → 481
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:500 → 550
    Reductase_C; Reductase C-terminal
    cl00938
    Location:108 → 152
    Rieske; Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. ...
    cl21454
    Location:184 → 273
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  12. XM_028827954.1 → XP_028683787.1  apoptosis-inducing factor 3 isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZCN9
    Conserved Domains (3) summary
    pfam07992
    Location:183 → 481
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:500 → 550
    Reductase_C; Reductase C-terminal
    cl00938
    Location:108 → 152
    Rieske; Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. ...

  13. XM_028827951.1 → XP_028683784.1  apoptosis-inducing factor 3 isoform X3

    UniProtKB/TrEMBL
    G7N3B3, H9FQE7
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  14. XM_028827950.1 → XP_028683783.1  apoptosis-inducing factor 3 isoform X3

    UniProtKB/TrEMBL
    G7N3B3, H9FQE7
    Related
    ENSMMUP00000067071.1, ENSMMUT00000087518.1
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:198 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal

  15. XM_028827952.1 → XP_028683785.1  apoptosis-inducing factor 3 isoform X4

    UniProtKB/TrEMBL
    G7N3B3
    Conserved Domains (3) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam07992
    Location:195 → 491
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:510 → 560
    Reductase_C; Reductase C-terminal
Nucleotide Protein
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