U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CTSB cathepsin B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 100424758, updated on 17-Aug-2024
Official Symbol
CTSBprovided by VGNC
Official Full Name
cathepsin Bprovided by VGNC
Primary source
VGNC:VGNC:71552
See related
Ensembl:ENSMMUG00000019212
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See CTSB in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (8711530..8736343)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (7866163..7892630)

Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene defensin beta 136 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function. Moon HY, et al. Cell Metab, 2016 Aug 9. PMID 27345423, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cathepsin B
XP_015000213.2
XP_015000214.2
XP_015000222.1
XP_028707930.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194899.2 → NP_001181828.2  cathepsin B precursor

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02000446
    UniProtKB/TrEMBL
    A0A1D5QVT4, F6QQ66, I0FJS6
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041761.1 Reference Mmul_10 Primary Assembly

    Range
    8711530..8736343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015144727.2 → XP_015000213.2  cathepsin B isoform X1

    UniProtKB/TrEMBL
    A0A1D5QVT4, F6QQ66, I0FJS6
    Related
    ENSMMUP00000076562.1, ENSMMUT00000093563.1
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  2. XM_028852097.1 → XP_028707930.1  cathepsin B isoform X1

    UniProtKB/TrEMBL
    A0A1D5QVT4, F6QQ66, I0FJS6
    Related
    ENSMMUP00000064385.1, ENSMMUT00000091570.1
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  3. XM_015144728.2 → XP_015000214.2  cathepsin B isoform X1

    UniProtKB/TrEMBL
    A0A1D5QVT4, F6QQ66, I0FJS6
    Related
    ENSMMUP00000052164.2, ENSMMUT00000060774.2
    Conserved Domains (2) summary
    cd02620
    Location:81 → 328
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam08127
    Location:26 → 65
    Propeptide_C1; Peptidase family C1 propeptide

  4. XM_015144736.2 → XP_015000222.1  cathepsin B isoform X2

    Conserved Domains (1) summary
    cd02620
    Location:25 → 204
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.