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MIR548T microRNA 548t [ Homo sapiens (human) ]

Gene ID: 100422849, updated on 2-Mar-2021

Summary

Official Symbol
MIR548Tprovided by HGNC
Official Full Name
microRNA 548tprovided by HGNC
Primary source
HGNC:HGNC:38298
See related
Ensembl:ENSG00000221296 miRBase:MI0014164
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Annotation information
Note: MIR548T (GeneID 100422849) was not annotated on NCBI's Build 37.3. Its correct location is chr4: NC_000004.11:174189311..174189384(+). [17 Jun 2014]
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Genomic context

See MIR548T in Genome Data Viewer
Location:
4q34.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (173268160..173268233)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (174189311..174189384)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase like 6 Neighboring gene uncharacterized LOC107986201 Neighboring gene uncharacterized LOC101930370 Neighboring gene RNA, 7SL, cytoplasmic 253, pseudogene Neighboring gene polypeptide N-acetylgalactosaminyltransferase 7 Neighboring gene uncharacterized LOC105377541 Neighboring gene high mobility group box 2

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036093.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC097534
    Related
    ENST00000408369.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    173268160..173268233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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