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macrod1.L MACRO domain containing 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100381041, updated on 4-Nov-2024

Summary

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Official Symbol
macrod1.L
Official Full Name
MACRO domain containing 1 L homeolog
Primary source
Xenbase:XB-GENE-6252561
Locus tag
XELAEV_18022219mg
See related
EnsemblRapid:ENSXLAG00005019971 AllianceGenome:Xenbase:XB-GENE-6252561
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
lrp16; macrod1
Summary
Predicted to enable ADP-ribosylglutamate hydrolase activity. Predicted to act upstream of or within DNA damage response; peptidyl-glutamate ADP-deribosylation; and purine nucleoside metabolic process. Predicted to be located in nucleoplasm. Orthologous to human MACROD1 (mono-ADP ribosylhydrolase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See macrod1.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (26680664..27117167)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (25157538..25593132)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing kindlin 3 L homeolog Neighboring gene stress induced phosphoprotein 1 L homeolog Neighboring gene uncharacterized LOC108696717 Neighboring gene fibronectin leucine rich transmembrane protein 1 L homeolog Neighboring gene uncharacterized LOC108713913 Neighboring gene OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
MACRO domain containing 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001174011.1 → NP_001167482.1  MACRO domain containing 1 L homeolog

    See identical proteins and their annotated locations for NP_001167482.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128925
    UniProtKB/TrEMBL
    A1A624
    Related
    ENSXLAP00005058573.1, ENSXLAT00005059976.1
    Conserved Domains (2) summary
    COG2110
    Location:80 → 240
    YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
    cd02908
    Location:75 → 241
    Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    26680664..27117167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589107.1 → XP_041445041.1  MACRO domain containing 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1MUA0
    Related
    ENSXLAP00005058565.1, ENSXLAT00005059965.1
    Conserved Domains (1) summary
    cd02908
    Location:75 → 241
    Macro_OAADPr_deacetylase; macrodomain, O-acetyl-ADP-ribose (OAADPr) family
Nucleotide Protein Strain
Heading Accession and Version

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