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PARK16 Parkinson disease 16 (susceptibility) [ Homo sapiens (human) ]

Gene ID: 100359403, updated on 7-Dec-2024
Gene symbol
PARK16
Gene description
Parkinson disease 16 (susceptibility)
See related
MIM:613164
Gene type
unknown
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Location:
1q32

Related articles in PubMed

  1. The effect of the PARK16 rs11240572 variant on brain structure in Parkinson's disease. Gu LY, et al. Brain Struct Funct, 2021 Nov. PMID 34373950
  2. Association of Parkinson disease to PARK16 in a Chilean sample. Ramirez A, et al. Parkinsonism Relat Disord, 2011 Jan. PMID 20934365
  3. An independent replication of PARK16 in Asian samples. Vilariño-Güell C, et al. Neurology, 2010 Dec 14. PMID 21172849, Free PMC Article
  4. [Association of PARK 16 polymorphisms with Parkinson's disease in Han population of Suzhou area]. Li DH, et al. Zhonghua Yi Xue Za Zhi, 2011 Feb 1. PMID 21419001
  5. Association between PARK16 and Parkinson's disease in the Han Chinese population: a meta-analysis. Chang KH, et al. Neurobiol Aging, 2013 Oct. PMID 23747047

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Parkinson's disease genome-wide association study-linked PARK16 variant is associated with a lower risk of cognitive impairment: A 4-year observational study.
    Title: Parkinson's disease genome-wide association study-linked PARK16 variant is associated with a lower risk of cognitive impairment: A 4-year observational study.
  2. The effect of the PARK16 rs11240572 variant on brain structure in Parkinson's disease.
    Title: The effect of the PARK16 rs11240572 variant on brain structure in Parkinson's disease.
  3. Within its limitations, this meta-analysis demonstrated that the rs823128 variants(G allele, GA and GG genotype)in PARK16 might be a potential protective factor for Parkinson's disease[meta-analysis]
    Title: Association between rs823128 polymorphism and the risk of Parkinson's disease: A meta-analysis.
  4. PARK16 locus rs947211 polymorphism (A allele, AG and GG genotype) may be a protective factor for PD in overall populations, particularly in Northeast Asian populations.
    Title: Association between PARK16 and Parkinson's disease: A meta-analysis.
  5. Interaction between LRRK2 and PARK16 loci variants do not influence risk of Parkinson's disease.
    Title: Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study.
  6. 1,144 individuals were screened for five SNPs in the PARK16 locus and logistic regression analysis showed that the A allele of the rs947211 SNP reduced the risk of developing Parkinson's disease (PD) via a recessive model. A allele of the rs947211 SNP decreased the risk of developing PD via a recessive model. Three SNPs (rs823128, rs823156, and rs11240572) reduced risk of developing PD via a dominant model.
    Title: PARK16 is associated with PD in the Malaysian population.
  7. The PARK16 SNPs rs823128, rs947211, and rs823156 and the CAAAC, TGAGA, and CAGAC haplotypes may be significantly associated with sporadic PD in Japan
    Title: PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan.
  8. Different PARK16 linkage disequilibrium patterns across Chinese, Japanese, Indian, Malay, and Caucasian groups.
    Title: Patterns of linkage disequilibrium at PARK16 may explain variances in genetic association studies.
  9. We also validated 2 new single-nucleotide polymorphisms, rs947211 and rs823144, in PARK16 to explore their association with susceptibility to PD
    Title: Association between PARK16 gene polymorphisms and susceptibility of Parkinson's disease in a Chinese population.
  10. Allelic heterogeneity at PARK16 appears a likely contributing factor in Parkinson disease.
    Title: Fine mapping and resequencing of the PARK16 locus in Parkinson's disease.
Submit: New GeneRIF Correction See all GeneRIFs (20)
Parkinson disease 16 (susceptibility)

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