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TTK TTK protein kinase [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100359213, updated on 17-Dec-2024

Summary

Gene symbol
TTK
Gene description
TTK protein kinase
See related
Ensembl:ENSOCUG00000007124
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

See TTK in Genome Data Viewer
Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 5 NC_091436.1 (92421799..92463152, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (88852672..88894020, complement)

Chromosome 5 - NC_091436.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC138849740 Neighboring gene branched chain keto acid dehydrogenase E1 subunit beta Neighboring gene calponin-3 pseudogene Neighboring gene tropomyosin alpha-3 chain pseudogene Neighboring gene ELOVL fatty acid elongase 4 Neighboring gene uncharacterized LOC127493015

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine/tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in meiotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mitotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein localization to kinetochore IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
dual specificity protein kinase TTK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091436.1 Reference mOryCun1.1

    Range
    92421799..92463152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008263144.4XP_008261366.1  dual specificity protein kinase TTK isoform X3

    UniProtKB/TrEMBL
    G1SSE5
    Related
    ENSOCUP00000006160.4
    Conserved Domains (2) summary
    cd14131
    Location:521789
    PKc_Mps1; Catalytic domain of the Dual-specificity Mitotic checkpoint protein kinase, Monopolar spindle 1 (also called TTK)
    pfam00069
    Location:523789
    Pkinase; Protein kinase domain
  2. XM_051854520.2XP_051710480.1  dual specificity protein kinase TTK isoform X1

  3. XM_051854521.2XP_051710481.1  dual specificity protein kinase TTK isoform X2