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PLK1 polo like kinase 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100356287, updated on 2-Dec-2024

Summary

Gene symbol
PLK1
Gene description
polo like kinase 1
See related
Ensembl:ENSOCUG00000008476
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

See PLK1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 19 NC_091450.1 (15664607..15678719, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 6 NC_067379.1 (14394743..14408834)

Chromosome 19 - NC_091450.1Genomic Context describing neighboring genes Neighboring gene protein kinase C beta Neighboring gene calcineurin like EF-hand protein 2 Neighboring gene endoplasmic reticulum to nucleus signaling 2 Neighboring gene dynactin subunit 5 Neighboring gene partner and localizer of BRCA2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in mitotic spindle organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine/threonine-protein kinase PLK1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091450.1 Reference mOryCun1.1

    Range
    15664607..15678719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002711849.5XP_002711895.1  serine/threonine-protein kinase PLK1

    UniProtKB/TrEMBL
    G1SV90
    Related
    ENSOCUP00000007325.2
    Conserved Domains (4) summary
    smart00220
    Location:58305
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13117
    Location:509590
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:407494
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14187
    Location:45309
    STKc_PLK1; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 1