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FGFR1 fibroblast growth factor receptor 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100351861, updated on 20-Feb-2025
Gene symbol
FGFR1
Gene description
fibroblast growth factor receptor 1
See related
Ensembl:ENSOCUG00000004150
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See FGFR1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 2 NC_091433.1 (88153408..88205674, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259158.1 (1258038..1309368, complement)

Chromosome 2 - NC_091433.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103352165 Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 2 Neighboring gene uncharacterized LOC103352164 Neighboring gene uncharacterized LOC103352163

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. VEGF-A/VEGFR-2 and FGF-2/FGFR-1 but not PDGF-BB/PDGFR-β play important roles in promoting immature and inflammatory intraplaque angiogenesis. Mao Y, et al. PLoS One, 2018. PMID 30125282, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
fibroblast growth factor receptor 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091433.1 Reference mOryCun1.1

    Range
    88153408..88205674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051832346.2 → XP_051688306.1  fibroblast growth factor receptor 1 isoform X10

    UniProtKB/TrEMBL
    A0A5F9DJS2

  2. XM_051832344.2 → XP_051688304.1  fibroblast growth factor receptor 1 isoform X8

    UniProtKB/TrEMBL
    A0A5F9DJS2

  3. XM_051832341.2 → XP_051688301.1  fibroblast growth factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F9C0P9, U3KNN6

  4. XM_051832342.2 → XP_051688302.1  fibroblast growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    U3KNN6

  5. XM_051832338.2 → XP_051688298.1  fibroblast growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    U3KNN6

  6. XM_008273978.4 → XP_008272200.1  fibroblast growth factor receptor 1 isoform X13

    UniProtKB/TrEMBL
    A0A5F9DJS2
    Conserved Domains (6) summary
    cd04974
    Location:180 → 269
    Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:73 → 157
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    smart00410
    Location:172 → 268
    IG_like; Immunoglobulin like
    pfam07679
    Location:70 → 157
    I-set; Immunoglobulin I-set domain
    cd05098
    Location:372 → 673
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam07714
    Location:386 → 662
    Pkinase_Tyr; Protein tyrosine kinase

  7. XM_051832347.2 → XP_051688307.1  fibroblast growth factor receptor 1 isoform X11

    UniProtKB/TrEMBL
    A0A5F9DJS2

  8. XM_070068555.1 → XP_069924656.1  fibroblast growth factor receptor 1 isoform X12

    UniProtKB/TrEMBL
    A0A5F9DJS2

  9. XM_051832345.2 → XP_051688305.1  fibroblast growth factor receptor 1 isoform X9

    UniProtKB/TrEMBL
    A0A5F9C7Y0, A0A5F9DJS2

  10. XM_008273975.4 → XP_008272197.1  fibroblast growth factor receptor 1 isoform X7

    UniProtKB/TrEMBL
    U3KNN6
    Conserved Domains (7) summary
    cd04973
    Location:41 → 119
    Ig1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd04974
    Location:269 → 358
    Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:162 → 246
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    smart00410
    Location:261 → 357
    IG_like; Immunoglobulin like
    pfam07679
    Location:159 → 246
    I-set; Immunoglobulin I-set domain
    cd05098
    Location:461 → 762
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam07714
    Location:475 → 751
    Pkinase_Tyr; Protein tyrosine kinase

  11. XM_051832343.2 → XP_051688303.1  fibroblast growth factor receptor 1 isoform X5

    UniProtKB/TrEMBL
    U3KNN6

  12. XM_008273974.4 → XP_008272196.1  fibroblast growth factor receptor 1 isoform X6

    UniProtKB/TrEMBL
    U3KNN6
    Conserved Domains (7) summary
    cd04973
    Location:41 → 119
    Ig1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd04974
    Location:271 → 360
    Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:164 → 248
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    smart00410
    Location:263 → 359
    IG_like; Immunoglobulin like
    pfam07679
    Location:161 → 248
    I-set; Immunoglobulin I-set domain
    cd05098
    Location:463 → 764
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam07714
    Location:477 → 753
    Pkinase_Tyr; Protein tyrosine kinase

  13. XM_051832340.2 → XP_051688300.1  fibroblast growth factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F9D998, U3KNN6

  14. XM_070068554.1 → XP_069924655.1  fibroblast growth factor receptor 1 isoform X8

    UniProtKB/TrEMBL
    A0A5F9DJS2

  15. XM_070068553.1 → XP_069924654.1  fibroblast growth factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F9C0P9, U3KNN6

  16. XM_051832339.2 → XP_051688299.1  fibroblast growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    U3KNN6

  17. XM_070068556.1 → XP_069924657.1  fibroblast growth factor receptor 1 isoform X13

    UniProtKB/TrEMBL
    A0A5F9DJS2
Nucleotide Protein
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